A5284
8-Azaguanine
Hybri-Max™, γ-irradiated, powder, BioXtra, suitable for hybridoma
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Synonym(s):
8-AzaG, 2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo
Empirical Formula (Hill Notation):
C4H4N6O
CAS Number:
Molecular Weight:
152.11
Beilstein:
171098
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
Recommended Products
grade
Hybri-Max™
sterility
γ-irradiated
product line
BioXtra
form
powder
technique(s)
cell culture | hybridoma: suitable
mp
>300 °C (lit.)
storage temp.
−20°C
SMILES string
NC1=Nc2[nH]nnc2C(=O)N1
InChI
1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChI key
LPXQRXLUHJKZIE-UHFFFAOYSA-N
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Application
For use in hybridoma cell culture applications as a myeloma selection agent.
Reconstitution
Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium.
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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July Fong et al.
Scientific reports, 8(1), 1155-1155 (2018-01-20)
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeting
Sunirmal Paul et al.
Environmental and molecular mutagenesis, 47(5), 311-319 (2006-03-07)
Endogenous DNA damage clusters--two or more oxidized bases, abasic sites, or strand breaks within about 20 base pairs on opposing strands--can accumulate in unirradiated mammalian cells, and may be significant origins of spontaneous detrimental biological effects. Factors determining the levels
M Schiltz et al.
Carcinogenesis, 20(12), 2279-2286 (1999-12-11)
Earlier studies have shown that the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (+)-BPDE at the hypoxanthine (guanine) phosphoribosyltransferase (hprt) gene of Chinese hamster V79 cells was dependent on the concentration of (+)-BPDE. In the present study, we examined the effect
Ziwei Li et al.
International journal of oncology, 52(6), 2079-2092 (2018-04-06)
Hepatocellular carcinoma (HCC) is one of the most common malignancies and causes of death worldwide. Research investigating novel therapeutic strategies for the treatment of HCC is urgently required. Monoclonal antibodies (mAbs) that target the programmed cell death‑1 (PD‑1/PDCD1)/programmed death-ligand 1
Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
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