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Merck
CN

A4003

Ala-Tyr

≥98% (TLC), suitable for mass spectrometry (MS)

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About This Item

Empirical Formula (Hill Notation):
C12H16N2O4
CAS Number:
Molecular Weight:
252.27
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
221-305-7
MDL number:
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Product Name

Ala-Tyr,

InChI key

ALZVPLKYDKJKQU-XVKPBYJWSA-N

InChI

1S/C12H16N2O4/c1-7(13)11(16)14-10(12(17)18)6-8-2-4-9(15)5-3-8/h2-5,7,10,15H,6,13H2,1H3,(H,14,16)(H,17,18)/t7-,10-/m0/s1

SMILES string

C[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

assay

≥98% (TLC)

form

powder

technique(s)

mass spectrometry (MS): suitable

color

white

storage temp.

−20°C

Quality Level

Gene Information

human ... SLC15A1(6564)

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Biochem/physiol Actions

Alanyl dipeptides such as ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Lihui Wei et al.
Nuclear medicine and biology, 36(3), 277-285 (2009-03-28)
The alpha(v)beta(3) integrin is a cell adhesion molecule known to be involved in stages of angiogenesis and metastasis. In this study, the chelators CB-TE2A and diamsar were conjugated to cyclic RGDyK and RGDfD and the biological properties of (64)Cu-labeled peptides
Efficient preparation and biological evaluation of a novel multivalency bifunctional chelator for 64Cu radiopharmaceuticals.
Shuanglong Liu et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 17(37), 10222-10225 (2011-08-05)
Hancheng Cai et al.
Dalton transactions (Cambridge, England : 2003), (27)(27), 5395-5400 (2009-07-01)
Copper-64 shows promise as both a suitable PET imaging and therapeutic radionuclide due to its nuclear characteristics. Stable attachment of radioactive (64)Cu(2+) to targeted imaging probes requires the use of a bifunctional chelator. Sarcophagine (Sar) ligands coordinate the metal ion
Michelle T Ma et al.
Bioconjugate chemistry, 22(10), 2093-2103 (2011-09-01)
Tumor-targeting peptides radiolabeled with positron-emitting (68)Ga are promising candidates as new noninvasive diagnostic agents for positron emission tomography (PET). The targeting peptides are tethered to a chelator that forms a stable coordination complex with Ga(3+) that is inert to dissociation
K Meylaers et al.
Current pharmaceutical design, 9(2), 159-174 (2003-02-07)
The number of bacterial and fungal strains that have developed resistance against the classical antibiotics continues to grow. The intensified search for new antibiotic lead compounds has resulted in the discovery of numerous endogenous peptides with antimicrobial properties in plants

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