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Safety Information

A3987

Sigma-Aldrich

Cefpodoxime proxetil

Synonym(s):

(RS)1(isopropoxycarbonyloxy) ethyl (+)-(6R,7R)-7-[2-(2-amino-4- thiazolyl)-2-{(Z)methoxyimino}acetamido]-3methoxymethyl-8-oxo-5-thia-1-azabicyclo [4.2.0]oct-2-ene- 2-carboxylate

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About This Item

Empirical Formula (Hill Notation):
C21H27N5O9S2
CAS Number:
87239-81-4
Molecular Weight:
557.60
UNSPSC Code:
51101500
NACRES:
NA.85

form

powder

storage temp.

−20°C

InChI

1S/C21H27N5O9S2/c1-9(2)33-21(30)35-10(3)34-19(29)15-11(6-31-4)7-36-18-14(17(28)26(15)18)24-16(27)13(25-32-5)12-8-37-20(22)23-12/h8-10,14,18H,6-7H2,1-5H3,(H2,22,23)(H,24,27)/b25-13-/t10?,14-,18-/m1/s1

InChI key

LTINZAODLRIQIX-FBXRGJNPSA-N

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Biochem/physiol Actions

Cefpodoxime proxetil is the esterified prodrug of cefpodoxime, a third-generation cephalosporin antibiotic with broad spectrum activity against most Gram-positive and Gram-negative bacteria. It inhibits bacterial cell wall synthesis by binding penicillin-binding proteins, preferentially penicillin binding protein 3, and resulting in the inhibition of peptidoglycan synthesis. Cefpodoxime is stable in the presence of most β-lactamase enzymes but inactivated by certain extended spectrum β-lactamases.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

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