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A3484

Sigma-Aldrich

Anti-ATG4A antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-APG4 autophagy 4 homolog A, Anti-APG4A, Anti-AUT-like 2, Anti-AUTL2, Anti-Autophagin 2, Anti-Autophagy related 4 homolog A, Anti-Autophagy-related cysteine endopeptidase 2, Anti-Cysteine endopeptidase, ATG4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~45 kDa

species reactivity

human

concentration

~1.0 mg/mL

technique(s)

immunoprecipitation (IP): 5-10 μg using lysate of HEK-293T cells

UniProt accession no.

Q8WYN0

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ATG4A(115201)

General description

Autophagy related 4A, cysteine peptidase (ATG4A or APG4A) is a C-54 cysteine protease that also belongs to the family of autophagin proteins. ATG4A is involved in cellular autophagy and has been studied as a target for cancer therapy. Rabbit anti-ATG4A antibody binds to human ATG4A.

Immunogen

synthetic peptide corresponding to amino acids 100-114 of human ATG4A, conjugated to KLH. The corresponding sequence differs by 2 amino acids in mouse and rat.

Application

Rabbit anti-ATG4A antibody can be used for immunoprecipitation assays at 5-10μg using HEK-293T cell lysates.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Certificates of Analysis (COA)

Lot/Batch Number
106M4760
049K4834

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Vidya Niranjan et al.
International journal of computational biology and drug design, 3(4), 271-286 (2011-02-08)
Autophagy is a biological process involved in the intracellular destruction of endogenous proteins and has been suggested to be essential for cell homeostasis as well as for cell remodelling. Autophagy selectively eradicates damaged cytoplasmic components like injured mitochondria, which increases

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