A3253
Ala-Pro hydrate
≥98% (TLC), suitable for ligand binding assays
Synonym(s):
L-Alanyl-L-proline hydrate
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About This Item
Empirical Formula (Hill Notation):
C8H14N2O3 · xH2O
CAS Number:
Molecular Weight:
186.21 (anhydrous basis)
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
236-795-8
MDL number:
Beilstein/REAXYS Number:
3546017
Product Name
Ala-Pro hydrate,
InChI
1S/C8H14N2O3.H2O/c1-5(9)7(11)10-4-2-3-6(10)8(12)13;/h5-6H,2-4,9H2,1H3,(H,12,13);1H2/t5-,6-;/m0./s1
InChI key
SSUWZOPYGFOQJA-GEMLJDPKSA-N
SMILES string
O.C[C@H](N)C(=O)N1CCC[C@H]1C(O)=O
assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
Quality Level
Related Categories
Biochem/physiol Actions
Alanyl dipeptides such as ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Pekka Mark et al.
European biophysics journal : EBJ, 36(3), 213-224 (2007-01-17)
Six different molecular dynamics simulations of Cyclophilin A, three with the protein free in water and three with the Ala-Pro dipeptide bound to the protein, have been performed, and analysed with respect to structure and hydration of the active site.
Justin F Shaffer et al.
Journal of muscle research and cell motility, 30(7-8), 303-306 (2010-03-11)
Cardiac myosin binding protein-C (cMyBP-C) is an accessory protein found in the A-bands of vertebrate sarcomeres and mutations in the cMyBP-C gene are a leading cause of familial hypertrophic cardiomyopathy. The regulatory functions of cMyBP-C have been attributed to the
R Hanai et al.
Journal of chromatography, 394(2), 273-278 (1987-05-22)
The "elution-band relaxation method" has been applied to the analysis of the cis-trans kinetics isomerization of the proline of L-Ala-L-Pro using reversed-phase liquid chromatography. A procedure suitable for cases where neither isomer can be injected separately is described.
I Naasani et al.
Biochimica et biophysica acta, 1231(2), 163-168 (1995-09-12)
The transport characteristics of ceftibuten, a dianionic cephem antibiotic, in rat renal and intestinal brush-border membranes were compared. Ceftibuten transport was mediated by two transport systems in the renal brush-border membrane and by one transport system in the intestinal brush-border
S Capasso et al.
Peptides, 19(2), 389-391 (1998-03-11)
Diketopiperazine formation from the N-terminal residues of a peptide chain is accelerated by aprotic dipolar protophobic solvents and catalyzed in organic solvents by alkylammonium carboxylate salts. The t1/2 for the first-order reaction of H-Ala-Pro-NH2 x TFA falls from 20 d
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