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Merck
CN

A3159

Adenine hemisulfate salt

powder, BioReagent, suitable for cell culture

Synonym(s):

6-Aminopurine hemisulfate salt, Adenine sulfate salt

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About This Item

Linear Formula:
C5H5N5 · 1/2H2SO4
CAS Number:
321-30-2
Molecular Weight:
184.17
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
24890722
EC Number:
206-286-5
Beilstein/REAXYS Number:
3820263
MDL number:
MFCD00213655

Key Documents

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Product Name

Adenine hemisulfate salt, powder, BioReagent, suitable for cell culture

InChI key

LQXHSCOPYJCOMD-UHFFFAOYSA-N

InChI

1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)

SMILES string

OS(O)(=O)=O.Nc1ncnc2[nH]cnc12.Nc3ncnc4[nH]cnc34

biological source

synthetic (organic)

product line

BioReagent

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

0.5 M HCl: 10 mg/mL

Quality Level

200

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Application

Adenine hemisulfate salt has been used:
  • as component of auxotrophy selection reagent for yeast culture
  • as essential nutrient to improve yeast transformation efficiency
  • as a component of synthetic complete (SC) medium for yeast culture

General description

Adenine is a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD). It is also part of flavin adenine dinucleotide (FAD) and signaling molecules cyclic adenosine monophosphate(cAMP).

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H319

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6042V
WXBF5636V
WXBF4737V
WXBF5112V
WXBF0756V

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Effect of preorganization on the affinity of synthetic DNA binding motifs for nucleotide ligands
Vollmer S and Richert C
Organic & Biomolecular Chemistry, 13(20), 5734-5742 (2015)
Mating based split-ubiquitin assay for detection of protein interactions
Horaruang W and Zhang B
Bio-protocol, 7, e2258-e2258 (2017)
Base-resolution stratification of cancer mutations using functional variomics
Yi S, et al.
Nature Protocols, 12(11), 2323-2323 (2017)
Nutrient supplements boost yeast transformation efficiency.
Yu SC, et al.
Scientific Reports, 6, 35738-35738 (2016)
Abigail R Lambert et al.
Structure (London, England : 1993), 28(7), 760-775 (2020-05-04)
The redesign of a macromolecular binding interface and corresponding alteration of recognition specificity is a challenging endeavor that remains recalcitrant to computational approaches. This is particularly true for the redesign of DNA binding specificity, which is highly dependent upon bending
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