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Merck
CN

A2795

N-Acetyl-D-galactosamine

≥98% (HPLC)

Synonym(s):

2-Acetamido-2-deoxy-D-galactose, D-GalNAc, N-Acetylchondrosamine

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About This Item

Empirical Formula (Hill Notation):
C8H15NO6
CAS Number:
Molecular Weight:
221.21
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
217-321-9
Beilstein/REAXYS Number:
2331340
MDL number:
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Product Name

N-Acetyl-D-galactosamine, ≥98% (HPLC)

InChI key

OVRNDRQMDRJTHS-KEWYIRBNSA-N

InChI

1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6+,7-,8?/m1/s1

SMILES string

CC(=O)N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O

assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable

color

white

mp

160 °C

solubility

water: 50 mg/mL, clear, colorless

storage temp.

2-8°C

Quality Level

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Application

N-Acetyl-D-galactosamine has been used:
  • as a Dolichos biflorus agglutinin (DBA) haptenic sugar in lectin bead binding assay
  • to assess the specificity of lectin binding using lectin blot inhibition
  • in immunohistochemistry to pre-adsorb Wisteria floribunda lectin

N-Acetyl-D-galactosamine (GalNAc), an aminosugar, is a component of many O-linked and N-linked glycan structures. As UDP-GalNAc, GalNAc is the intial O-linked sugar to many serine and threonine residues in protein glycosylations.

General description

N-Acetyl-D-galactosamine (GalNAc), an amino sugar, is a component of many O-linked and N-linked glycan structures. As uridine diphosphate (UDP)-GalNAc, GalNAc is the initial O-linked sugar to many serine and threonine residues in protein glycosylations.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Malte Lenders et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 32(12), 2090-2097 (2016-09-30)
Renal and cardiac involvement is responsible for substantial morbidity and mortality in Fabry disease (FD). We analysed the incidence of FD-related renal, cardiac and neurologic end points in patients with FD on long-term enzyme replacement therapy (ERT). A retrospective analysis
Ju Huang et al.
Molecular therapy. Methods & clinical development, 5, 241-258 (2017-06-13)
Fabry disease is a rare lysosomal storage disorder (LSD). We designed multiple recombinant lentivirus vectors (LVs) and tested their ability to engineer expression of human α-galactosidase A (α-gal A) in transduced Fabry patient CD34
Dezemon Zingue et al.
Scientific reports, 8(1), 6778-6778 (2018-05-02)
Contaminations and fastidiousness of M. ulcerans may have both hamper isolation of strains from environmental sources. We aimed to optimize decontamination and culture of environmental samples to circumvent both limitations. Three strains of M. ulcerans cultured onto Middlebrook 7H10 at
Kai J Rogers et al.
PLoS neglected tropical diseases, 13(12), e0007819-e0007819 (2019-12-12)
Ebolavirus (EBOV) outbreaks, while sporadic, cause tremendous morbidity and mortality. No therapeutics or vaccines are currently licensed; however, a vaccine has shown promise in clinical trials. A critical step towards development of effective therapeutics is a better understanding of factors
F H M van Zelst et al.
Faraday discussions, 218(0), 219-232 (2019-05-24)
To detect and characterise compounds in complex matrices, it is often necessary to separate the compound of interest from the matrix before analysis. In our previous work, we have developed the coupling of supercritical fluid chromatography (SFC) with nuclear magnetic

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