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Merck
CN

A2522

Actin from rabbit muscle

≥85% (SDS-PAGE), lyophilized powder

Synonym(s):

Alpha-actin 1, G-Actin

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About This Item

CAS Number:
51005-14-2
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
MFCD00130338

Key Documents

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Product Name

Actin from rabbit muscle, ≥85% (SDS-PAGE), lyophilized powder

biological source

rabbit

assay

≥85% (SDS-PAGE)

form

lyophilized powder

mol wt

43 kDa

composition

Protein, ≥80% biuret

technique(s)

immunoblotting: suitable

UniProt accession no.

P68135

storage temp.

2-8°C

Quality Level

200

Gene Information

rabbit ... LOC(100342017)

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Application

Actin from rabbit muscle has been used:
  • to study its protective role on rabbit muscle lactate dehydrogenase from ascorbate inhibition
  • as standard in SDS gel and immunoblotting
  • in the protein pin array assays

Biochem/physiol Actions

Actin plays a key role in protein-protein interactions. It participates in cell motility, cell shape maintenance and polarity to the regulation of transcription.

General description

Actin is the abundant protein found in many cells which accounts for 10% or more of total protein. Most of the eukaryotic cells shows the presence of actin protein. Outer and inner domains are the two important domains of actin.

Physical form

Lyophilized powder containing Tris, ATP and CaCl2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
SLCF6381
SLCH1369
021M7672
096K7034
093K7025

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Actin and Actin-Binding Proteins
Pollard TD, et al.
Cold Spring Harbor Perspectives in Biology, 8(8) (2016)
Desmin cytoskeletal modifications after a bout of eccentric exercise in the rat
Barash IA, et al.
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 91-98 (2002)
Pooneh Vaziri et al.
Genetics, 216(1), 177-190 (2020-08-06)
Myosin is an essential motor protein, which in muscle is comprised of two molecules each of myosin heavy-chain (MHC), the essential or alkali myosin light-chain 1 (MLC1), and the regulatory myosin light-chain 2 (MLC2). It has been shown previously that MLC2
J A Henderson et al.
Endocrine, 33(3), 285-293 (2008-11-21)
To further understand the role of ovarian hormones in the function of the serotonin neural system, we investigated the effects of estradiol (E), progesterone (P), and raloxifene on 5HT 1A and 2C receptor protein expression in the dorsal raphe region
Jarrod A Call et al.
Journal of applied physiology (Bethesda, Md. : 1985), 105(3), 923-932 (2008-06-28)
Duchenne muscular dystrophy is characterized by the absence of dystrophin from muscle cells. Dystrophic muscle cells are susceptible to oxidative stress. We tested the hypothesis that 3 wk of endurance exercise starting at age 21 days in young male mdx
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Articles

Actin Protein

Actin isoforms are muscle tissue markers; six isoforms expressed, four for muscle differentiation, two ubiquitous.

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