A2513
N-Acetyl-L-tyrosine
>99% (TLC)
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About This Item
Linear Formula:
4-(HO)C6H4CH2CH(NHCOCH3)CO2H
CAS Number:
Molecular Weight:
223.23
EC Number:
208-671-3
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
2697172
MDL number:
InChI key
CAHKINHBCWCHCF-JTQLQIEISA-N
InChI
1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1
SMILES string
CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
assay
>99% (TLC)
storage temp.
−20°C
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Investigation of DNA-protein cross-link formation between lysozyme and oxanine by mass spectrometry.
Hauh-Jyun Candy Chen et al.
Chembiochem : a European journal of chemical biology, 9(7), 1074-1081 (2008-03-21)
Reactive nitrogen species are implicated in inflammatory diseases and cancers. Oxanine (Oxa) is a DNA lesion product originating from the guanine base through exposure to nitric oxide, nitrous acid, or N-nitrosoindoles. Oxanine was found to mediate formation of DNA-protein cross-links
G Drabik et al.
Acta biochimica Polonica, 48(1), 271-275 (2001-07-07)
N-acetyl-L-tyrosine (N-acTyr), with the alpha amine residue blocked by acetylation, can mimic the reactivity of exposed tyrosyl residues incorporated into polypeptides. In this study chlorination of N-acTyr residue at positions 3 and 5 in reactions with NaOCl, chloramines and the
M Lehnig
Archives of biochemistry and biophysics, 393(2), 245-254 (2001-09-15)
During reaction of N-acetyl-l-tyrosine with the nitrating system (15)NO(-)(2)/H(2)O(2)/HRP at pH 7.5, emission is observed in the (15)N NMR signals of 3-nitro-N-acetyl-l-tyrosine and the 1-nitrocyclohexa-2,5-dien-4-one derivative of N-acetyl-l-tyrosine. The occurrence of (15)N CIDNP proves the formation of radical pairs. The
T Nishiyama et al.
Journal of biochemistry, 127(3), 427-433 (2000-03-25)
It was previously revealed [Yamaguchi, H., Nishiyama, T., and Uchida, M. (1999) J. Biochem. 126, 261-265] that N-glycans of both the high-mannose and complex types have binding affinity for aromatic amino acid residues. This study shows that free N-glycans protect
David I Pattison et al.
Biochemistry, 45(26), 8152-8162 (2006-06-28)
Hypochlorous acid (HOCl) is a powerful oxidant generated from H(2)O(2) and Cl(-) by the heme enzyme myeloperoxidase, which is released from activated leukocytes. HOCl possesses potent antibacterial properties, but excessive production can lead to host tissue damage that is implicated
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