A2394
Acetylcholine perchlorate
Synonym(s):
ACh
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About This Item
Empirical Formula (Hill Notation):
C7H16ClNO6
CAS Number:
Molecular Weight:
245.66
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
213-166-6
MDL number:
Gene Information
human ... CHRM3(1131)
InChI key
SHIQLFRCVFUYEK-UHFFFAOYSA-M
InChI
1S/C7H16NO2.ClHO4/c1-7(9)10-6-5-8(2,3)4;2-1(3,4)5/h5-6H2,1-4H3;(H,2,3,4,5)/q+1;/p-1
SMILES string
[O-]Cl(=O)(=O)=O.CC(=O)OCC[N+](C)(C)C
assay
≥98.0% (TLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless
storage temp.
−20°C
Application
Acetylcholine is an endogenous neurotransmitter at cholinergic synapses that amplifies action potential of the sarcolemma thereby inducing muscle contractions.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Aswin Verhoeven et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 168(2), 314-326 (2004-05-14)
It is demonstrated that internuclear distances can be evaluated from rotational-resonance (RR) experiments in uniformly (13)C-labelled compounds. The errors in the obtained distances are less than 10% without the need to know any parameters of the spin system except the
Saikat Ray et al.
Science (New York, N.Y.), 343(6173), 891-896 (2014-01-25)
Little is known about how microcircuits are organized in layer 2 of the medial entorhinal cortex. We visualized principal cell microcircuits and determined cellular theta-rhythmicity in freely moving rats. Non-dentate-projecting, calbindin-positive pyramidal cells bundled dendrites together and formed patches arranged
Xun Qian et al.
Arteriosclerosis, thrombosis, and vascular biology, 34(1), 127-135 (2013-11-02)
Intermediate and small conductance KCa channels IK1 (KCa3.1) and SK3 (KCa2.3) are primary targets of endothelial Ca(2+) signals in the arterial vasculature, and their ablation results in increased arterial tone and hypertension. Activation of IK1 channels by local Ca(2+) transients
Yingchuan B Qi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(12), 5319-5325 (2013-03-22)
Excitatory acetylcholine motor neurons drive Caenorhabditis elegans locomotion. Coordinating the activation states of the backward-driving A and forward-driving B class motor neurons is critical for generating sinusoidal and directional locomotion. Here, we show by in vivo calcium imaging that expression
Jeppe A Olsen et al.
The Journal of biological chemistry, 288(50), 35997-36006 (2013-10-31)
Positive allosteric modulators (PAMs) of α4β2 nicotinic acetylcholine receptors have the potential to improve cognitive function and alleviate pain. However, only a few selective PAMs of α4β2 receptors have been described limiting both pharmacological understanding and drug-discovery efforts. Here, we
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