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A1422

Sigma-Aldrich

p-Aminohippuric acid

≥99%

Synonym(s):

4-Aminohippuric acid, N-(4-Aminobenzoyl)glycine

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About This Item

Linear Formula:
NH2C6H4C(O)NHCH2COOH
CAS Number:
61-78-9
Molecular Weight:
194.19
Beilstein:
1213676
EC Number:
200-518-9
MDL number:
MFCD00007890
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24890544
NACRES:
NA.26

product name

p-Aminohippuric acid, ≥99%

Quality Level

200

Assay

≥99%

form

powder

mp

199-200 °C (dec.) (lit.)

application(s)

cell analysis

storage temp.

room temp

SMILES string

Nc1ccc(cc1)C(=O)NCC(O)=O

InChI

1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13)

InChI key

HSMNQINEKMPTIC-UHFFFAOYSA-N

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General description

Renal tubules secretes para amino hippuric acid/PAH.

Application

p-Aminohippuric acid has been used as infusions to measure plasma flow.

Biochem/physiol Actions

Para-Aminohippuric acid (PAH), OAT-1 specific, is used to help differentiate and characterized organic anion transporter (OAT) isoforms.
Para-aminohippuric acid (PAH) is used as a marker in nutrition studies to measure the flow of blood in pigs, which inturn helps to determine the portal-drained viscera (PDV) flux of nutrients.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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In vivo measurement of nitric oxide production in porcine gut, liver and muscle during hyperdynamic endotoxaemia
Bruins MJ, et al.
British Journal of Pharmacology, 137(8), 1225-1236 (2002)
Intragastric bolus feeding of meals containing elementary, partially hydrolyzed or intact protein causes comparable changes in interorgan substrate flux in the pig
Deutz NEP, et al.
Clinical Nutrition (Edinburgh, Scotland), 15(3), 119-128 (1996)
Effect of prolonged hyperdynamic endotoxemia on jejunal motility in fasted and enterally fed pigs
Bruins MJ, et al.
Annals of Surgery, 237(1), 44-44 (2003)
Glomerular Filtration
Quantitative Human Physiology, 633-641 (2012)
Influence of para-aminohippuric acid analysis on net portal-drained viscera flux of nutrients in pigs
Fernandez-FI, et al.
Animal : An International Journal of Animal Bioscience, 12(2), 232-238 (2018)
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