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Merck
CN

A0627

Adenosine-5′-diphosphoglucose disodium salt

≥93%, from yeast, powder

Synonym(s):

ADP, ADP-Glucose, ADP-glc, ADPG

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About This Item

Empirical Formula (Hill Notation):
C16H23N5Na2O15P2
CAS Number:
Molecular Weight:
633.31
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
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Product Name

Adenosine-5′-diphosphoglucose disodium salt, ≥93%

SMILES string

[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OC4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@H]3O

InChI

1S/C16H25N5O15P2.2Na/c17-13-7-14(19-3-18-13)21(4-20-7)15-11(26)9(24)6(33-15)2-32-37(28,29)36-38(30,31)35-16-12(27)10(25)8(23)5(1-22)34-16;;/h3-6,8-12,15-16,22-27H,1-2H2,(H,28,29)(H,30,31)(H2,17,18,19);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,15-,16?;;/m1../s1

InChI key

GZBIVALVIPYODS-UQGWVDHFSA-L

biological source

yeast

assay

≥93%

form

powder

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

Quality Level

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Application

Adenosine-5′-diphosphoglucose (ADP-Glucose) is a substrate widely used as a glucose donor. It is a substrate in starch synthesis by starch synthase (EC 2.4.1.21). ADP-Glucose is a substrate for alpha-1,4-glucan-protein synthase (ADP-forming) (EC 2.4.1.113), ADP-glucose pyrophosphorylases and many glucosyltransferases.
Adenosine-5′-diphosphoglucose disodium salt has been used as a component of the reaction mixture to measure the enzymatic activity of adenosine-5′-diphosphate (ADP)-glucose pyrophosphorylase (AGPase) and for the synthesis of starch.

Biochem/physiol Actions

Adenosine-5′-diphosphoglucose (ADP-Glucose) is a substrate widely used as a glucose donor. It is a substrate starch synthase (EC 2.4.1.21) in starch synthesis. ADP-glucose is a substrate for α-1,4-glucan-protein synthase (ADP-forming) (EC 2.4.1.113), ADP-glucose pyrophosphorylases and many glucosyltransferases.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Analysis of Starch Synthase Activities in Wheat Grains using Native-PAGE
Li Z
Bio-protocol (2016)
Xinqiao Zhan et al.
Scientific reports, 7(1), 4685-4685 (2017-07-07)
Seed setting is an important trait that contributes to seed yield and relies greatly on starch accumulation. In this study, a sulfoquinovosyl transferase-like protein, designated as SQD2.2 involved in seed setting and flavonoid accumulation, was identified and characterized in rice.
Steven Ball et al.
Journal of experimental botany, 62(6), 1775-1801 (2011-01-12)
Solid semi-crystalline starch and hydrosoluble glycogen define two distinct physical states of the same type of storage polysaccharide. Appearance of semi-crystalline storage polysaccharides appears linked to the requirement of unicellular diazotrophic cyanobacteria to fuel nitrogenase and protect it from oxygen
Mengyao Xue et al.
Rice (New York, N.Y.), 12(1), 100-100 (2020-01-01)
The endosperm of rice (Oryza sativa) has been usually used for the study of starch synthesis. Although several related factors have been revealed, other unknown members remain to be identified, given that starch synthesis is a complicated and sophisticated process.
José G Vallarino et al.
Scientific reports, 10(1), 17219-17219 (2020-10-16)
The capacity to assimilate carbon and nitrogen, to transport the resultant sugars and amino acids to sink tissues, and to convert the incoming sugars and amino acids into storage compounds in the sink tissues, are key determinants of crop yield.

Articles

LC-MS/MS method quantifies similar polar nucleotide activated sugars using Supel™ Carbon LC column for simultaneous analysis.

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