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A0278

Sigma-Aldrich

L-Ascorbic acid

reagent grade

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Synonym(s):
L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
50-81-7
Molecular Weight:
176.12
Beilstein:
84272
EC Number:
200-066-2
MDL number:
MFCD00064328
UNSPSC Code:
12352209
PubChem Substance ID:
24890417
NACRES:
NA.26

biological source

synthetic

Quality Level

200

grade

reagent grade

Assay

≥98% (with Iodine, titration)

form

powder

technique(s)

HPLC: suitable

color

white to light yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

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General description

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. It is a water-soluble vitamin.

Application

L-Ascorbic acid has been used as a standard in high performance liquid chromatography (HPLC) for quantification of L-ascorbic acid.
L-Ascorbic acid may be used as standard in assay for erythrocyte hemolysis mediated by peroxyl free radicals. It may be used for the reduction of graphene oxide sheets.

Biochem/physiol Actions

L-Ascorbic acid is an anti-oxidant. L-Ascorbic acid (vitamin C) is important for many enzymatic reactions for maintaining prosthetic metal ions in their reduced forms (for example, Fe2+, Cu+). It protects tissues from oxidative damage by scavenging free radicals. It has mild reductive ability and nontoxic property. It is commonly employed reductant in the laboratory. Colorimetric determination of ascorbic acid in plasma using acid phosphotungstate has been reported.
L-ascorbic acid modified poly(ester urethane)s might facilitate soft tissue regeneration. It also helps in increasing iron absorption by tissues. In addition, it aids in tyrosine metabolism and microsomal drug metabolism.

Caution

May darken in storage.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis and characterization of cycloaliphatic hydrophilic polyurethanes, modified with L-ascorbic acid, as materials for soft tissue regeneration
Kucinska-Lipka J, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 75(3), 671-681 (2017)
Solubilities of magnesium-l-ascorbate, calcium-l-ascorbate, magnesium-l-glutamate, magnesium-d-gluconate, calcium-d-gluconate, calcium-d-heptagluconate, l-aspartic acid, and 3-nitrobenzoic acid in water
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