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Key Documents

A0207

Sigma-Aldrich

(+)-Iron(II) L-ascorbate

≥90% (titration)

Synonym(s):

L-(+)-Ascorbic acid iron(II) salt, Ferrous ascorbate, Vitamin C iron(II) salt

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About This Item

Empirical Formula (Hill Notation):
C12H14FeO12
CAS Number:
Molecular Weight:
406.08
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.79

Assay

≥90% (titration)

form

crystalline

color

dark brown

SMILES string

[H][C@@]1(OC(=O)C(O)=C1O[Fe]OC2=C(O)C(=O)O[C@]2([H])[C@@H](O)CO)[C@@H](O)CO

InChI

1S/2C6H8O6.Fe/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1

InChI key

RFBYLSCVRUTUSB-ZZMNMWMASA-L

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Biochem/physiol Actions

(+)-Iron(II) L-ascorbate or ferrous ascorbate has high potential to absorb iron in vivo compared to ferrous sulfate. In children, it is used as an effective oral iron supplement to treat iron deficiency anemia.
Iron-ascorbate (ferrous-ascorbate) is used as a reagent in cell culture and other systems to evaluate various aspects of oxidative stress and anti-oxidation mechanisms.

Caution

May darken in storage.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hanne Vorwerk et al.
Molecular microbiology, 98(5), 809-830 (2015-08-12)
Thermophilic Campylobacter species colonize the intestine of agricultural and domestic animals commensally but cause severe gastroenteritis in humans. In contrast to other enteropathogenic bacteria, Campylobacter has been considered to be non-glycolytic, a metabolic property originally used for their taxonomic classification.
Hanne Vorwerk et al.
Molecular microbiology, 93(6), 1224-1245 (2014-07-31)
The non-glycolytic food-borne pathogen Campylobacter jejuni successfully colonizes the intestine of various hosts in spite of its restricted metabolic properties. While several amino acids are known to be used by C. jejuni as energy sources, none of these have been
Bartosz Rózanowski et al.
Investigative ophthalmology & visual science, 49(7), 2838-2847 (2008-03-11)
To determine the effects of human retinal pigment epithelial (RPE) cell pigment granules on photosensitized and iron ion-mediated oxidation and the effect of the photodegradation of melanosomes on their antioxidant properties. RPE cells were isolated from human and bovine eyes;
Complex stability of ferrous ascorbate in aqueous solution and its significance for iron absorption
Plug CM, et al.
Pharmaceutisch Weekblad. Scientific Edition, 6(6), 245-248 (1984)
Treatment of iron deficiency anemia in children: a comparative study of ferrous ascorbate and colloidal iron
Yewale V N and Dewan B
Indian Journal of Pediatrics, 80(5), 385-390 (2013)

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