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U1006

Uridine 5′-triphosphate trisodium salt solution

Name: Uridine 5′-triphosphate trisodium salt solution
Brand: SIGMA

HPLC purified, aqueous solution for RNA polymerase transcription

Synonym(s):

UTP

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About This Item

NACRES:

NA.52

PubChem Substance ID:

24900622

UNSPSC Code:

41106305

MDL number:

MFCD00044310

Assay:

≥95 (HPLC)

Biological source:

yeast (Candida Utilis)

Form:

liquid

Storage temp.:

−20°C

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Properties

biological source

yeast (Candida Utilis)

Quality Level

300

assay

≥95 (HPLC)

form

liquid

concentration

100 mM in H₂O (adjusted to pH 7 with Trizma^®
base)

technique(s)

cDNA synthesis: suitable

color

colorless

foreign activity

DNase and RNase, none detected

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1

InChI key

MMJGIWFJVDOPJF-LLWADOMFSA-K

Gene Information

human ... P2RY2(5029)
rat ... P2ry2(29597)

Description

Application

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

Biochem/physiol Actions

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

P2Y receptor agonist

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000494158

0000375452

SLCN0184

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Global Trade Item Number

SKU	GTIN
U1006-25UMO	04061833655573