S4019
Sodium bicarbonate
Hybri-Max™, powder, suitable for hybridoma, ≥99.5%
Synonym(s):
Sodium hydrogen carbonate
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About This Item
Linear Formula:
NaHCO3
CAS Number:
Molecular Weight:
84.01
UNSPSC Code:
12161702
NACRES:
NA.75
PubChem Substance ID:
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
grade
Hybri-Max™
assay
≥99.5%
form
powder
technique(s)
cell culture | hybridoma: suitable
impurities
endotoxin, tested
pH
8.3 (0.1 molfreshly prepared)
pKa (25 °C)
(1) 6.37, (2) 10.25 (carbonic acid)
solubility
water: soluble 100 mg/mL
density
2.16 g/mL at 25 °C (lit.)
SMILES string
[Na+].OC([O-])=O
InChI
1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
InChI key
UIIMBOGNXHQVGW-UHFFFAOYSA-M
Application
Sodium bicarbonate has been used as a supplement:
- in minimum essential medium (MEM)/flushing medium for embryo isolation
- in TCM 199 medium for the collection of cumulus-oocyte complexes (COCs) and in vitro maturation (IVM)
- in IVM medium for in vitro maturation of COCs
Biochem/physiol Actions
Sodium bicarbonate occurs naturally as the mineral nahcolite. It is used to prepare many sodium salts as well as a carbon dioxide source. Sodium bicarbonate is used in the manufacture of fire extinguishers and cleaning agents. Bicarbonate plays an important role in pH regulation in vivo. In biochemistry, molecular biology, and chromatography, sodium bicarbonate is used as a buffer. This Hybri-Max™ product is suitable for use in hybridoma and cell culture research (2.2 mg/ml).
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The effect of estrous ewe serum and heparin on in vitro fertilization and subsequent embryonic development in sheep
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The effects of L-ergothioneine and L-ascorbic acid on the in vitro maturation (IVM) and embryonic development (IVC) of sheep oocytes
Development, 1, 5-14 (2010)
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S4019-1KG | 04061836924607 |
| S4019-500G | 04061836924744 |