P9180
Procaterol hydrochloride
β2 adrenoceptor agonist, powder
Synonym(s):
erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1H)-quinolinone
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About This Item
Empirical Formula (Hill Notation):
C16H22N2O3 · HCl
CAS Number:
Molecular Weight:
326.82
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
263-763-0
MDL number:
Product Name
Procaterol hydrochloride,
InChI key
AEQDBKHAAWUCMT-CVHDTDHSSA-N
InChI
1S/C16H22N2O3.ClH/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15;/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20);1H/t12-,16+;/m0./s1
SMILES string
Cl.CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c2NC(=O)C=Cc12
form
powder
storage temp.
2-8°C
Quality Level
Related Categories
General description
Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.
Biochem/physiol Actions
β2-adrenoceptor agonist; bronchodilator.
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
监管及禁止进口产品
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Nobuyo Komatani-Tamiya et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 29(3-4), 511-522 (2012-04-18)
The beating cilia play a key role in lung mucociliary transport. The ciliary beating frequency (CBF) and ciliary bend amplitude (CBA) of isolated mouse bronchiolar ciliary cells were measured using a light microscope equipped with a high-speed camera (500 Hz).
Immune System Diseases: New Insights for the Healthcare Professional (2012)
Y Yamazaki et al.
British journal of pharmacology, 124(3), 593-599 (1998-07-01)
1. The beta-adrenoceptor (beta-AR) subtypes mediating relaxation of the rabbit, rat and canine detrusors were subjected to functional investigation using selective beta-AR agonists and antagonists. 2. In all three species, isoprenaline, noradrenaline and adrenaline each produced a concentration-dependent relaxation of
Ching-Hua Huang et al.
Pediatric pulmonology, 45(10), 977-984 (2010-07-31)
Procaterol is a β2-adrenoceptor agonist used as a bronchodilator for the treatment of asthma; it also possesses an anti-inflammatory property. As chemokines play a pivotal role in inflammation and the pathogenesis of asthma, we investigated the effects of procaterol on
Ethanolamines: Advances in Research and Application (2012)
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