N8000
1-Naphthyl butyrate
esterase substrate, ≥99% (GC), liquid
Synonym(s):
Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester
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About This Item
Linear Formula:
CH3CH2CH2CO2C10H7
CAS Number:
Molecular Weight:
214.26
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
221-500-7
MDL number:
Beilstein/REAXYS Number:
2558646
Product Name
1-Naphthyl butyrate, esterase substrate
Quality Level
assay
≥99% (GC)
form
liquid
refractive index
n20/D 1.571 (lit.)
bp
125-130 °C/1 mmHg (lit.)
solubility
ethanol: 100 mg/mL, clear, colorless to faintly yellow
density
1.091 g/mL at 20 °C (lit.)
storage temp.
−20°C
SMILES string
CCCC(=O)Oc1cccc2ccccc12
InChI
1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3
InChI key
XIVJNRXPRQKFRZ-UHFFFAOYSA-N
General description
Esterase substrate.
Application
1-Naphthyl butyrate has been used as a substrate for esterase activity in sheep body louse Bovicola ovis and in chromogenic staining of flounder fish samples.
Biochem/physiol Actions
1-Naphthyl butyrate also called α-naphthyl butyrate is a substrate for esterase enzyme. α-naphthyl butyrate aids in assessing α-naphthyl butyrate esterase activity in monocytes and lymphocytes.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
143.6 °F - closed cup
flash_point_c
62 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Identification of alpha-naphthyl butyrate esterase as a plasma membrane ectoenzyme of monocytes and as a discrete intracellular membrane-bounded organelle in lymphocytes.
Bozdech MJ and Bainton DF
The Journal of Experimental Medicine, 153(1), 182-195 (1981)
T Honda et al.
Histochemistry, 77(3), 299-302 (1983-01-01)
The proteases of human leukocytes were cytochemically studied by use of new alpha-naphthyl esters, tosyl-L-lysine-alpha-naphthyl ester (TLNE) and acetyl-L-tyrosine-alpha-naphthyl ester (ATNE). The hydrolytic activities were strong only in neutrophils, with both substrates. They were inhibited completely by DFP and chymostatin
M S Levine et al.
Journal of occupational medicine. : official publication of the Industrial Medical Association, 28(3), 207-211 (1986-03-01)
A cross-sectional review of routine employee health status examinations has identified an undercounting of circulating monocytes associated with an inhibition of a surface monocyte esterase, alpha-naphthyl butyrate esterase. It is postulated that this inhibition is associated with an organophosphate used
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N8000-1G | 04061834118305 |
| N8000-10G | 04061832918273 |
| N8000-250MG | 04061834118312 |
| N8000-5G | 04061832918297 |