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H6750

Hippuryl-Lys

Name: Hippuryl-Lys
Brand: SIGMA

Synonym(s):

N-Benzoyl-Gly-Lys

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₁N₃O₄

CAS Number:

740-63-6

Molecular Weight:

307.34

NACRES:

NA.32

PubChem Substance ID:

24895759

UNSPSC Code:

12352204

MDL number:

MFCD00038208

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Properties

assay

≥98% (TLC)

Quality Level

200

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NCCCCC(NC(=O)CNC(=O)c1ccccc1)C(O)=O

InChI

1S/C15H21N3O4/c16-9-5-4-8-12(15(21)22)18-13(19)10-17-14(20)11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,16H2,(H,17,20)(H,18,19)(H,21,22)

InChI key

LRCZLURYHGISRZ-UHFFFAOYSA-N

Description

General description

Substrate for carboxypeptidase B and carboxypeptidase N.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Isolation and purification of creatine kinase conversion factor from human serum and its identification as carboxypeptidase N.

L Michelutti et al.

Clinical biochemistry, 20(1), 21-29 (1987-02-01)

Creatine kinase conversion factor has been isolated from human serum and purified to electrophoretic and chromatographic homogeneity. The enzyme sequentially converts creatine kinase MM3 to MM2 and MM1 and hydrolyzes lysine and arginine from hippuryl-L-lysine and hippuryl-L-arginine. Data on molecular

Rapid assay of human plasma carboxypeptidase N by high-performance liquid chromatographic separation of hippuryl-lysine and its product.

F Marceau et al.

Journal of chromatography, 266, 173-177 (1983-08-26)

A rapid and sensitive method for measuring carboxypeptidase N (CPN) activity in human plasma is described. The procedure is based on the hydrolysis of a high-specificity/low-affinity substrate, hippuryl-L-lysine, to its products hippuric acid and lysine. The substrate and product are

Reaction of N(alpha)-hippuryllysine with 2-hydroxyheptanal: a model for lysine-directed protein modifications by lipid peroxidation.

Koichi Itakura et al.

Chemistry and physics of lipids, 124(2), 81-88 (2003-06-24)

2-Hydroxyheptanal (2-HH) is one of the major aldehydes derived from peroxidation of polyunsaturated fatty acids. In the present study, to obtain an insight into the contributions of 2-HH to protein modifications during lipid peroxidation, a lysine-containing dipeptide, N(alpha)-hippuryllysine (N-benzoylglycyl-L-lysine, BGL)

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Global Trade Item Number

SKU	GTIN
H6750-1G	04061833801765