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Sigma-Aldrich

D-α-Tocopherol succinate

BioXtra, ≥98.0% (HPLC)

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Synonym(s):
Vitamin E succinate
Empirical Formula (Hill Notation):
C33H54O5
CAS Number:
4345-03-3
Molecular Weight:
530.78
Beilstein:
4038233
EC Number:
224-403-8
MDL number:
MFCD00072055
UNSPSC Code:
12352211
PubChem Substance ID:
57653662
NACRES:
NA.79

product line

BioXtra

Quality Level

100

Assay

≥98.0% (HPLC)

form

powder

color

white to faint yellow

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1

InChI

1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1

InChI key

IELOKBJPULMYRW-NJQVLOCASA-N

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General description

Tocopherol is a lipid soluble vitamin E. It is present in food sources, such as soybean, almond oil, sunflower oil. Tocopherol has four isoforms in plants, which are α, β, γ and δ. It is composed of a chromanol ring with varied position of methyl group. D-αTocopherol succinate is also known as vitamin E succinate (VES).

Biochem/physiol Actions

Tocopherol exhibits antioxidant property by protecting the cells and membranes from oxidative stress. In plants, high levels of α-tocopherol leads to plant stress tolerance whereas low levels is associated with oxidative stress. In humans, tocopherol prevents cancer, premature aging, atherosclerosis, arthritis caused due to free radicals. Vitamin E succinate (VES) is an anti-tumor analog of vitamin E.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Specialty oils: functional and nutraceutical properties
Functional Dietary Lipids, 67, 69-101 (2016)
Tocopherols and tocotrienols in plants and their products: A review on methods of extraction, chromatographic separation, and detection
Saini, R K and Keum Y S
Food Research International, 82, 59-70 (2016)
Implications of light energy on food quality and packaging selection
Advances in Food and Nutrition Research, 67, 25-73 (2012)
Tocopherol succinate: a promising radiation countermeasure.
Singh VK, Brown DS, Kao TC.
International Journal of Immunopharmacology, 9, 1423-1430 (2009)
Xuhui Zhang et al.
The British journal of nutrition, 104(12), 1796-1805 (2010-09-03)
The anti-inflammatory effects of two esters of a-tocopherol (α-TOH), all-rac-α-TOH acetate (DL-α-TOA) and RRR-α-TOH succinate (D-α-TOS), on broilers repeatedly challenged with lipopolysaccharide (LPS) were investigated. Three hundred and twenty 1-d-old broiler chicks were allotted into four treatment groups and fed
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