94261
LL-37 (human) trifluoroacetate salt
≥95% (HPLC)
Synonym(s):
Human LL-37 amide Trifluoroacetate
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About This Item
Empirical Formula (Hill Notation):
C205H341N61O52 · xC2HF3O2
Molecular Weight:
4492.28 (free base basis)
NACRES:
NA.85
UNSPSC Code:
51101500
Product Name
LL-37 (human) trifluoroacetate salt, ≥95% (HPLC)
assay
≥95% (HPLC)
form
powder (Lyophilisate)
color
colorless to white
solubility
H2O: 1 mg/mL, clear, colorless
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
viruses
mode of action
cell membrane | interferes
storage temp.
−20°C
Quality Level
Related Categories
Application
LL-37 is used to study host defense mechanisms.
Biochem/physiol Actions
LL-37 is a muntifunctional host defense peptide with antibacterial, antiviral, and immunomodulating activities. It is the only cathelicidin-type peptide found in human. In addition to its antimicrobial activities, LL-37 has been found to regulate inflammation and neutralize lipopolysaccharides from Gram-negative bacteria.
General description
Chemical structure: peptide
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. Keep in a dry place.
Packaging
1mg
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
涉药品监管产品
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Ainhoa Revilla-Guarinos et al.
Applied and environmental microbiology, 86(14) (2020-05-18)
Bce-like systems mediate resistance against antimicrobial peptides in Firmicutes bacteria. Lactobacillus casei BL23 encodes an "orphan" ABC transporter that, based on homology to BceAB-like systems, was proposed to contribute to antimicrobial peptide resistance. A mutant lacking the permease subunit was
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