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Merck
CN

93394

Trizma® Buffer substance

pH 9.0

Synonym(s):

Tris Buffer substance, Tris(hydroxymethyl)aminomethane Buffer substance

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About This Item

UNSPSC Code:
12161700
PubChem Substance ID:
57653554
MDL number:
MFCD00012590

Key Documents

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InChI

1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

SMILES string

Cl.NC(CO)(CO)CO

InChI key

QKNYBSVHEMOAJP-UHFFFAOYSA-N

form

powder or crystals

mol wt

average mol wt 124.6

pH

8.7±0.1 (37 °C, 0.05 M), 9.0±0.1 (25 °C, 0.05 M), 9.6±0.1 (5 °C, 0.05 M)

solubility

H2O: 0.67 g/mL, clear, colorless

General description

Trizma® and its salts are used as biological buffers to control the pH of body fluids in vitro and in vivo. It acts as a precursor for polymers, oxazolones (with carboxylic acids), and oxazolidines (with aldehydes). Trizma can serve as an alkalizing agent in treating acidosis of the blood.

Application

Trizma® Buffer substance has been used as an eluent in asymmetrical flow field-flow fractionation (AFFFF).

Legal Information

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBN1864V
BCBL9857V
BCBL9206V
BCBL8401V
BCBD8042V

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K Kolokassidou et al.
Journal of hazardous materials, 164(2-3), 442-447 (2008-09-20)
Disposed olive cake generates hydrophilic components that can be mobilized in the aquatic environment. This paper deals with the characterization of such components, isolated by alkaline extraction. It is shown that these substances possess properties very much resembling humic acid

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