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90878

Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 300

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.26

Quality Level

product line

BioUltra

form

viscous liquid

mol wt

Mr 285-315

impurities

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

refractive index

n20/D 1.465

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL at 25 °C, clear, colorless

density

1.125 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Application


  • Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: This study explores the use of Poly(ethylene glycol) (PEG) in creating a lyophilized eukaryotic cell-free protein expression system. The research demonstrates how PEG facilitates the stabilization and preservation of cell-free systems, enhancing protein synthesis capabilities for various biochemical applications (Alfaro-Palma et al., 2024).

  • High-Contrast Luminescent Immunohistochemistry Using PEGylated Lanthanide Complexes.: The application of PEGylated lanthanide complexes in immunohistochemistry significantly improves the contrast and specificity of luminescent signals. This innovation aids in more accurate biochemical analysis and diagnostics (Su et al., 2022).

  • Analyzing Immune Response to Engineered Hydrogels by Hierarchical Clustering of Inflammatory Cell Subsets.: This research investigates the immune responses to PEG-based hydrogels used in tissue engineering. It provides insights into the biocompatibility and inflammatory reactions, essential for designing advanced biomaterials (Fernandez-Yague et al., 2022).

  • Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood.: The study shows how PEGylation of nanoparticles affects their interaction with immune cells, influencing drug delivery systems and therapeutic efficacy in biochemistry and molecular biology (Ju et al., 2020).

  • A Post-Insertion Strategy for Surface Functionalization of Bacterial and Mammalian Cell-Derived Extracellular Vesicles.: This paper discusses the post-insertion method using PEG for surface functionalization of extracellular vesicles, enhancing their potential for targeted drug delivery and biochemical research (Jiang et al., 2021).

WGK

WGK 1

Flash Point(F)

281.5 °F

Flash Point(C)

138.6 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene

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