All Photos(1)
Synonym(s):
10-Acetyl-3,7-dihydroxyphenoxazine
Empirical Formula (Hill Notation):
C14H11NO4
CAS Number:
Molecular Weight:
257.24
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
Recommended Products
grade
for fluorescence
Quality Level
Assay
≥98.0% (HPLC)
form
powder
fluorescence
λex 571 nm; λem 585 nm in DMSO
storage temp.
2-8°C
SMILES string
CC(=O)N1c2ccc(O)cc2Oc3cc(O)ccc13
InChI
1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3
InChI key
PKYCWFICOKSIHZ-UHFFFAOYSA-N
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Application
Ampliflu™ Red has been used to study mitochondrial abnormalities and oxidative stress related to Parkinson’s Disease. Ampliflu™ Red assay was suitable as an alternative indicator assay for detecting the inhibition of hTPO (human thyroid peroxidase) activity. Phospholipase D, an essential cellular process ingredient, used Ampliflu™ Red (10-Acetyl-3,7-dihydroxyphenoxazine) to determine its activity.Ampliflu™ Red is used for the following applications:
- Quantification of inflammatory mediators
- Determination of free and esterified cholesterol contents
- Evaluation of compounds as substrates for GABA-AT compounds
Legal Information
Ampliflu is a trademark of Sigma-Aldrich Co. LLC
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Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Barae Jomaa et al.
ALTEX, 32(3), 191-200 (2015-03-31)
A simple and rapid luminometric assay for the detection of chemical inhibitors of human thyroid peroxidase (hTPO) activity was developed and validated with 10 model compounds. hTPO was derived from the human thyroid follicular cell line Nthy-ori 3-1 and its
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Macrophages may be a crucial aspect of diabetic complications associated with the inflammatory response. In this study, we examined how hyperglycaemia, a common aspect of diabetes, modulates bone marrow-derived macrophages (BMDMs) under an inflammatory stimulus. To perform this study, BMDMs
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Chemistry (Weinheim an der Bergstrasse, Germany), 24(63), 16865-16872 (2018-08-29)
Cetyl-trimethylammonium bromide (CTAB) is a widely used cationic surfactant that is biodegradable in nature. CTAB biodegradation requires hydroxylation in the first step, which is rate-limiting and crucial for solubility in water. In this study, the OmniChange multi-site mutagenesis method was
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