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Safety Information

88997

Sigma-Aldrich

6-Carboxy-tetramethylrhodamine N-succinimidyl ester

BioReagent, suitable for fluorescence

Synonym(s):

"5-Carboxytetramethylrhodamine N-succinimidyl ester"

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About This Item

Empirical Formula (Hill Notation):
C29H25N3O7
CAS Number:
150810-69-8
Molecular Weight:
527.52
MDL number:
MFCD03453266
UNSPSC Code:
12352202
NACRES:
NA.21

product line

BioReagent

Quality Level

200

form

powder

solubility

DMF: 2 mg/mL, clear
acetonitrile: soluble

fluorescence

λex 543 nm; λem 575 nm in 0.1 M phosphate pH 7.0

suitability

suitable for fluorescence

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

SMILES string

[N+](=[c]1cc2[o]c3c(c(c2cc1)c4c(ccc(c4)C(=O)ON5C(=O)CCC5=O)C(=O)[O-])ccc(c3)N(C)C)(C)C

InChI

1S/C29H25N3O7/c1-30(2)17-6-9-20-23(14-17)38-24-15-18(31(3)4)7-10-21(24)27(20)22-13-16(5-8-19(22)28(35)36)29(37)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3

InChI key

PAOQTZWNYMMSEE-UHFFFAOYSA-N

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Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Fluorescent labeling of peptides after chemical modification; Fluorescent labeling of aminoglycoside antibiotics

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH9344
BCCG4438
BCCD7485
BCCD4062
BCCC5423

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Y Wang et al.
Biochemistry, 35(38), 12338-12346 (1996-09-24)
RNA aptamers had previously been selected which were able to bind to the aminoglycoside antibiotic tobramycin with high affinity (Wang & Rando, 1995). Consensus sequences are found in a variety of constructs, and these sequences were mapped to stem-loop regions
P Hoogerhout et al.
The journal of peptide research : official journal of the American Peptide Society, 54(5), 436-443 (1999-11-24)
The mechanism which enables lipopeptides to induce cytotoxicity is not known. By preparing fluorescent-labeled lipopeptides one might unravel the mechanism of their entry into the cell and their intracellular pathway. A method of preparing double-fluorescent-labeled peptides by solid-phase chemistry is
S.J. Bark et al.
Journal of the American Chemical Society, 122, 3567-3567 (2000)

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