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Merck
CN

88930

Thionin acetate salt

suitable for microscopy

Synonym(s):

3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet

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About This Item

Empirical Formula (Hill Notation):
C12H9N3S · C2H4O2
CAS Number:
78338-22-4
Molecular Weight:
287.34
PubChem Substance ID:
57653323
UNSPSC Code:
12352200
NACRES:
NA.25
MDL number:
MFCD00081194
Colour Index Number:
52000
Beilstein/REAXYS Number:
4345073

Key Documents

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SMILES string

CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1

InChI

1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1

InChI key

OWXBIRAFHWASMS-UHFFFAOYSA-M

form

powder

technique(s)

titration: suitable

suitability

suitable for microscopy

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Application

Thionine (Lauth′s violet), a metachromatic dye, is widely used as a biological stain of materials such as DNA. Thionine is being studied as an electron mediator in the development of microbial fuel cells and electrochemical biosensors.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF7101
BCCD4028
BCCB6762
BCBW0602
BCBT3723

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Liu Deng et al.
Analytical chemistry, 82(10), 4283-4287 (2010-04-21)
In this work we developed a fully integrated biofuel cell on a microchip, which consisted of glucose dehydrogenase supported (carbon nanotubes/thionine/gold nanoparticles)(8) multilayer as the anode, and the (carbon nanotubes/polylysine/laccase)(15) multilayer as the cathode. The as-obtained biofuel cell produced open
Ling Meng et al.
Biosensors & bioelectronics, 24(6), 1751-1756 (2008-10-24)
A glutamate biosensor based on the electrocatalytic oxidation of reduced nicotinamide adenine dinucleotide (NADH), which was generated by the enzymatic reaction, was developed via employing a single-walled carbon nanotubes/thionine (Th-SWNTs) nanocomposite as a mediator and an enzyme immobilization matrix. The
Limei Zhu et al.
Biosensors & bioelectronics, 35(1), 507-511 (2012-04-10)
A novel protocol for development of DNA electrochemical biosensor based on thionine-graphene nanocomposite modified gold electrode was presented. The thionine-graphene nanocomposite layer with highly conductive property was characterized by scanning electron microscopy, transmission electron microscopy, cyclic voltammetry and electrochemical impedance
Yanyan Cai et al.
Biosensors & bioelectronics, 36(1), 6-11 (2012-05-09)
Interests in using nanoporous metals for biosensing applications have been increasing. Herein, nanotubular mesoporous PdCu (NM-PdCu) alloy is used to fabricate a novel label-free electrochemical immunosensor for cancer biomarker carcinoembryonic antigen (CEA). It operates through physisorption of anti-CEA on NM-PdCu
Zhoumin Sun et al.
Analytica chimica acta, 761, 84-91 (2013-01-15)
In this paper, we fabricate a sensitive and stable amperometric UA amperometric biosensor using nanobiocomposite derived from thionine modified graphene oxide in this study. A simple wet-chemical strategy for synthesis of thionine-graphene oxide hybrid nanosheets (T-GOs) through π-π stacking has
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