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Safety Information

87128

Sigma-Aldrich

Tetracycline

98.0-102.0% (HPLC)

Synonym(s):

Tetracycline HCL, Tetracycline Monohydrochloride

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Select a Size

100 ML
CN¥1,498.09
500 ML
CN¥2,810.55
1 L
CN¥4,127.56
2.5 L
CN¥9,821.96
6 X 500 ML
CN¥14,044.07
4 L
CN¥15,403.82
6 X 1 L
CN¥16,723.15
4 X 4 L
CN¥59,211.22
18 L
CN¥67,272.08

CN¥1,498.09

Available to ship onApril 25, 2025Details

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100 ML
CN¥1,498.09
500 ML
CN¥2,810.55
1 L
CN¥4,127.56
2.5 L
CN¥9,821.96
6 X 500 ML
CN¥14,044.07
4 L
CN¥15,403.82
6 X 1 L
CN¥16,723.15
4 X 4 L
CN¥59,211.22
18 L
CN¥67,272.08

About This Item

Empirical Formula (Hill Notation):
C22H24N2O8 · xH2O
CAS Number:
60-54-8
Molecular Weight:
444.43 (anhydrous basis)
Beilstein:
2230417
EC Number:
200-481-9
MDL number:
MFCD00151232
UNSPSC Code:
51284017
PubChem Substance ID:
57653229
NACRES:
NA.85

CN¥1,498.09

Available to ship onApril 25, 2025Details

Request a Bulk Order

biological source

synthetic

Quality Level

200

Assay

98.0-102.0% (HPLC)

form

powder or crystals

color

faint yellow to dark yellow

mp

172-174 °C (dec.)

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

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This Item
911410911429911399
Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide) PEG average Mn 5,000, PLGA average Mn 25,000, lactide:glycolide 50:50

799041

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) PEG average Mn 5,000, PLGA average Mn 10,000, lactide:glycolide 80:20

911410

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) PEG average Mn 5,000, PLGA average Mn 5,000, lactide:glycolide 80:20

911429

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) PEG average Mn 2,000, PLGA average Mn 10,000, lactide:glycolide 80:20

911399

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)

form

powder

form

powder

form

powder

form

powder or chunks

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

mol wt

PEG average Mn 5,000

mol wt

PEG average Mn 5,000 (by NMR), PLGA average Mn 10,000 (by NMR)

mol wt

PEG average Mn 5,000 (by NMR), PLGA average Mn 5,000 (by NMR)

mol wt

PEG average Mn 2,000 (by NMR), PLGA average Mn 10,000 (by NMR)

composition

lactide:glycolide 50:50

composition

-

composition

-

composition

-

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

100

General description

Chemical structure: tetracycline

Biochem/physiol Actions

Mode of Action: Tetracycline passively diffuses through proin channels in the cell membrane, binding to 30S ribosomes and inhibits protein synthesis by preventing access of aminoacyl tRNA to the acceptor site on the mRNA-ribosome complex. It also binds to the bacterial 50S ribosomal subunit, altering the membrane and causing intracellular components to leak from bacterial cells. The inhibitory effects can be reversed by washing, suggesting that it is the reversibly bound antibiotic, and not the irreversibly bound drug, that is responsible for antibacterial action.

Mode of Resistance: The effects are inactivated via a loss of cell wall permeability.

Antimicrobial spectrum: Includes a wide range of antimicrobial activity against gram-positive and gram-negative bacteria.

Packaging

25g, 100g

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Hygroscopic. Light sensitive. Keep in a dry place.

related product

Product No.
Description
Pricing

Signal Word

Warning

Hazard Statements

H302,H361fd,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品
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    Lot/Batch Number
    0000395313
    0000384412
    0000384412
    0000395313
    0000223580

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