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Merck
CN

86694

Tetraethylene glycol monododecyl ether

BioXtra, ≥98.0% (GC)

Synonym(s):

C12E4, Dodecyl tetraethylene glycol ether, Dodecyltetraglycol

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About This Item

Linear Formula:
CH3(CH2)11(OCH2CH2)4OH
CAS Number:
5274-68-0
Molecular Weight:
362.54
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
57653173
EC Number:
226-097-1
Beilstein/REAXYS Number:
1791369
MDL number:
MFCD00043063

Key Documents

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Product Name

Tetraethylene glycol monododecyl ether, BioXtra, ≥98.0% (GC)

InChI key

WPMWEFXCIYCJSA-UHFFFAOYSA-N

InChI

1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCO

description

non-ionic

product line

BioXtra

assay

≥98.0% (GC)

form

liquid

mol wt

362.54 g/mol

refractive index

n20/D 1.450-1.454

mp

1.67 °C

density

0.946 g/mL at 20 °C (lit.)

cation traces

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cr: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤50 mg/kg
Mg: ≤50 mg/kg
Mn: ≤50 mg/kg
Na: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

Quality Level

100

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Application

Tetraethylene glycol monododecyl ether (C12E4) has been used:


  • as a water-soluble surfactant in computational and physical experiments to report the post-deposition motion of the surfactant front and the deformation of the subphase surface using Marangoni flow and capillary waves
  • to study its mixed micellization and interfacial properties in the absence and presence of sodium propionate
  • to investigate the phase transformation of C12E4 aqueous solutions by Rayleigh light scattering (RLS) when adopting different heating ways

General description

Tetraethylene glycol monododecyl ether (C12E4) is a nonionic surfactant. It is used as a stabilizer in several phase behavior and evaporation studies. This polyoxyethylated lauryl ether surfactant is a water-soluble surfactant.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM8044
BCCG3344
BCCB7496
BCBV4309
BCBN6553V

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Aijaz A Dar et al.
Journal of colloid and interface science, 298(1), 395-405 (2005-12-28)
Mixed micelle formation and interfacial properties of aqueous binary surfactant combinations of dodecyltrimethylammonium bromide (C12TAB) and tetraethyleneglycol mono-n-dodecyl ether (C12E4) at 30 degrees C in absence and presence of sodium propionate (NaPr) have been investigated. The critical micelle concentration, aggregation
N Taulier et al.
Biophysical journal, 78(2), 857-865 (2000-02-02)
We have used a lamellar phase made of a nonionic surfactant, dodecane and water, as a model membrane to investigate its interactions with macromolecular inclusions bringing together two membranes, i.e., acting as macromolecular snaps. In systems devoid of inclusions, the
Jun Sawayama et al.
Langmuir : the ACS journal of surfaces and colloids, 27(14), 8653-8658 (2011-06-09)
By mixing a small volume of THF containing guanosine derivative 1 and tetraethylenegrycol dodecyl ether (TEGDE) with water and subsequently removing TEGDE by gel permeation chromatography, micrometer-sized giant unilamellar vesicles (GUV) of 1 were successfully prepared. The vesicle membrane was
D J Kerr et al.
European journal of cancer & clinical oncology, 23(9), 1315-1322 (1987-09-01)
The effects of a non-ionic polyoxyethylated lauryl ether surfactant (Brij 30) on monolayer uptake and spheroid penetration of adriamycin have been studied. Co-incubation of adriamycin with Brij 30 increases intracellular adriamycin levels by 2-3-fold. Although, in the concentrations used, Brij
Rajib Kumar Mitra et al.
The journal of physical chemistry. B, 112(41), 12946-12953 (2008-09-24)
In this contribution, we attempt to correlate the change in water dynamics in a reverse micellar (RM) core caused by the modification of the interface by mixing an anionic surfactant, sodium bis(2-ethylhexyl) sulfosuccinate (AOT), and a nonionic surfactant, tetraethylene glycol
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