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84110

Sigma-Aldrich

Sucrose monolaurate

BioXtra, ≥97.0% (TLC)

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Synonym(s):
n-Dodecanoylsucrose, Lauric acid sucrose ester, Sucrose monododecanoate
Empirical Formula (Hill Notation):
C24H44O12
CAS Number:
25339-99-5
Molecular Weight:
524.60
Beilstein:
65819
EC Number:
246-873-3
MDL number:
MFCD00077947
UNSPSC Code:
12161900
PubChem Substance ID:
57652988
NACRES:
NA.25

description

non-ionic

Quality Level

100

product line

BioXtra

Assay

≥97.0% (TLC)

form

powder

mol wt

524.60 g/mol

impurities

≤3% water

CMC

0.3

cation traces

Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤1000 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC(=O)OC[C@H]1O[C@H](O[C@]2(CO)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C24H44O12/c1-2-3-4-5-6-7-8-9-10-11-17(27)33-13-16-18(28)20(30)21(31)23(34-16)36-24(14-26)22(32)19(29)15(12-25)35-24/h15-16,18-23,25-26,28-32H,2-14H2,1H3/t15-,16-,18-,19-,20+,21-,22+,23-,24+/m1/s1

InChI key

KGUHOFWIXKIURA-VQXBOQCVSA-N

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General description

Sucrose monolaurate is a non-ionic detergent and a carbohydrate fatty acid monoester. It is generally used for the solubilization of membrane proteins.

Application

Sucrose monolaurate has been used as an antimicrobial agent. It has also been used as a constituent of lysis buffer to homogenize placental tissues for determining serine palmitoyltransferase (SPT) activity.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

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Levente Kürti et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(3), 445-454 (2012-01-26)
Sucrose esters are effective solubilizers and there is an interest to use them as pharmaceutical excipients for nasal drug delivery. We have determined for the first time the non-toxic doses of laurate and myristate sucrose esters by four independent methods
Shan He et al.
PloS one, 14(5), e0216816-e0216816 (2019-05-31)
The high heat and mass transfer, and controlled mechanoenergy, in angled vortex fluidics has been applied in chemical and material sciences and allied fields, but its utility in food processing remains largely unexplored. Herein we report three models of food
Mitsugu Shimobayashi et al.
Molecular biology of the cell, 24(6), 870-881 (2013-02-01)
The evolutionarily conserved Orm1 and Orm2 proteins mediate sphingolipid homeostasis. However, the homologous Orm proteins and the signaling pathways modulating their phosphorylation and function are incompletely characterized. Here we demonstrate that inhibition of nutrient-sensitive target of rapamycin complex 1 (TORC1)
Non-reducing trisaccharide fatty acid monoesters: novel detergents in membrane biochemistry
Perez-Victoria I, et al.
Biochimica et Biophysica Acta - Biomembranes, 1808(3), 717-726 (2011)
Angéla Szuts et al.
International journal of pharmaceutics, 410(1-2), 107-110 (2011-03-23)
This study focused on an investigation of the applicability of sucrose laurate as surfactant in solid dispersions. Although this surfactant has a US Drug Master File, it has not been used so far in internal pharmaceutical products. High drug-loaded solid
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