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Merck
CN

81227

Poly(ethylene glycol)

greener alternative

BioUltra, 3,000

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
NACRES:
NA.26
PubChem Substance ID:
24887699
UNSPSC Code:
12352104
MDL number:
MFCD00081839

Key Documents

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Product Name

Poly(ethylene glycol), BioUltra, 3,000

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

SMILES string

C(CO)O

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

product line

BioUltra

form

solid

mol wt

Mr 2700-3300

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

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impurities

insoluble matter, passes filter test
≤0.001% peroxides (as H2O2)

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

solubility

H2O: 50 mg/mL at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

UV absorption

λ: 260 nm Amax: 0.09
λ: 280 nm Amax: 0.03

greener alternative category

Aligned

Quality Level

200

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Application

Poly(ethylene glycol) (PEG) has been used to study PEG-β lactoglobulin interaction. It has also been used to study the interaction of serum albumins with PEG.

General description

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

281.5 °F - closed cup

flash_point_c

138.6 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF7978
BCBJ1777V
1414532

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Microscopic and thermodynamic analysis of PEG??-lactoglobulin interaction.
Bekale L, et al.
Royal Society of Chemistry Advances, 4, 31084-31093 (2014)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Katrin K, et al.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
L Bekale et al.
Colloids and surfaces. B, Biointerfaces, 130, 141-148 (2015-04-14)
We investigated the interaction between polyethylene (glycol) (PEG) and human (HSA) and bovine serum albumin (BSA) in aqueous solution, using multiple spectroscopic methods and molecular modeling. The two important polymer characteristics, size and PEG hydrophobic end-group are studied in order
Mark A Rice et al.
Acta biomaterialia, 5(1), 152-161 (2008-09-17)
Ultrasound has potential as a non-destructive analytical technique to provide real-time online assessments of matrix evolution in cell-hydrogel constructs used in tissue engineering. In these studies, chondrocytes were encapsulated in poly(ethylene glycol) hydrogels, and gel degradation was manipulated to provide
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