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Merck
CN

78544

Glucose tetrasaccharide

≥99.0% (TLC)

Synonym(s):

Glcα1-6Glcα1-4Glcα1-4Glc

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About This Item

Empirical Formula (Hill Notation):
C24H42O21
CAS Number:
35175-16-7
Molecular Weight:
666.58
NACRES:
NA.28
PubChem Substance ID:
329768157
UNSPSC Code:
12352201
MDL number:
MFCD09840666

Key Documents

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InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-10(29)12(31)17(36)23(43-8)45-20-7(3-27)42-24(18(37)14(20)33)44-19-6(2-26)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21?,22+,23-,24-/m1/s1

SMILES string

OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)C(O)O[C@@H]4CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI key

FPBCRLIOSBQLHS-QVTSYAGHSA-N

assay

≥99.0% (TLC)

form

powder

color

white

suitability

corresponds for LC-MS

storage temp.

room temp

Quality Level

100

Related Categories

Application

Glucose tetrasaccharide (Glc4) is used as a reference in analysis of urinary glucose tetrasacchaide, a biomarker for Pompe disease and other glycogen storage diseases.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1270
BCCN3624
BCCM8759
BCCM6429
BCCK6038

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Unique oligosaccharide (apparently glucotetrasaccharide) in urine of patients with glycogen storage diseases.
K Oberholzer et al.
Clinical chemistry, 36(7), 1381-1381 (1990-07-01)
Chihiro Yonee et al.
Brain & development, 34(10), 834-839 (2012-04-24)
Pompe disease is an autosomal recessive disorder caused by deficiency of the lysosomal enzyme, acid alpha-glucosidase (GAA). To the best of our knowledge, no studies have reported the results of systematic and sequential CT analyses before and during ERT. In
D A Zopf et al.
Journal of immunological methods, 48(1), 109-119 (1982-01-01)
A radioimmunoassay is described that allows rapid determination of a urinary oligosaccharide -- Glc alpha 1-6Glc alpha 1-4Glc alpha 1-4Glc [(Glc)4] -- at concentrations greater than 2 pmol/microliter. Antibodies produced in rabbits immunized with the phenethylamine derivative of (Glc)4 coupled
Johannes Brettschneider et al.
Journal of neuroimmunology, 217(1-2), 95-101 (2009-11-03)
The serum level of IgM antibodies against Glc(alpha1,4)Glc(alpha) (GAGA4) is higher in relapsing remitting multiple sclerosis (RRMS) compared to other neurological disease (OND) patients and healthy controls (HC). Detecting the level of anti-GAGA4 antibody by enzyme immunoassay and total IgM
Mikael Schwarz et al.
Journal of the neurological sciences, 244(1-2), 59-68 (2006-02-17)
There is an unmet need to develop specific biomarkers for multiple sclerosis (MS) to aid in the diagnosis, improve the management of patients and the monitoring of the effectiveness of treatment. We have screened serum from patients with relapsing-remitting MS
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