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Merck
CN

75436

L-Ribulose

≥90% (HPLC)

Synonym(s):

L-Adonose, L-erythro-2-Pentulose

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
Molecular Weight:
150.13
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
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InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h3,5-8,10H,1-2H2/t3-,5-/m0/s1

SMILES string

OC[C@H](O)[C@H](O)C(=O)CO

InChI key

ZAQJHHRNXZUBTE-UCORVYFPSA-N

assay

≥90% (HPLC)

form

liquid

optical activity

[α]/D +14.5±3.0°, c = 0.1 in H2O

storage temp.

2-8°C

Quality Level

Application

L-Ribulose has been used as a substrate in L-arabinose isomerase activity assay and in ribulokinase activity assay.

Biochem/physiol Actions

L-Ribulose is produced from L-ribose by microbial enzymes. L-Ribulose is a rare sugar and a precursor for antiviral drugs synthesis. Major industrial production of L-ribulose is by the use of L-arabinose isomerase enzyme.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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L-Ribulose: a novel chiral pool compound.
Vanhessche, K., et al.
Tetrahedron Letters, 31, 2337-2340 (1990)
Kenji Morimoto et al.
Journal of bioscience and bioengineering, 115(4), 377-381 (2012-12-05)
A newly isolated bacterium, Cellulomonas parahominis MB426, produced l-ribose isomerase (CeLRI) on a medium containing l-ribose as a sole carbon source. A 32 kDa protein isomerizing l-ribose to l-ribulose was purified to homogeneity from this bacterium. A set of degenerated
Ye-Wang Zhang et al.
Applied microbiology and biotechnology, 87(6), 1993-1999 (2010-05-25)
Recombinant Escherichia coli harboring the L: -arabinose isomerase (BLAI) from Bacillus licheniformis was used as a biocatalyst to produce L: -ribulose in the presence of borate. Effects of substrate concentration, the borate to L: -arabinose ratio, pH, and temperature on
Cassandra De Muynck et al.
Journal of chromatography. A, 1101(1-2), 115-121 (2005-10-29)
A new high performance liquid chromatographic (HPLC) method is described for the analysis of ribose, arabinose and ribulose mixtures obtained from (bio)chemical isomerization processes. These processes gain importance since the molecules can be used for the synthesis of antiviral therapeutics.
M Helanto et al.
Applied and environmental microbiology, 73(21), 7083-7091 (2007-09-18)
L-Ribulose is a rare and expensive sugar that can be used as a precursor for the production of other rare sugars of high market value such as L-ribose. In this work we describe a production process for L-ribulose using L-arabinose

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