75068
9,10-Anthracenediyl-bis(methylene)dimalonic acid
BioReagent, suitable for fluorescence, ≥90% (HPCE)
Synonym(s):
ABDA, Single Oxygen Probe
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About This Item
Empirical Formula (Hill Notation):
C22H18O8
CAS Number:
Molecular Weight:
410.37
UNSPSC Code:
12352106
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3503804
Product Name
9,10-Anthracenediyl-bis(methylene)dimalonic acid, BioReagent, suitable for fluorescence, ≥90% (HPCE)
InChI
1S/C22H18O8/c23-19(24)17(20(25)26)9-15-11-5-1-2-6-12(11)16(10-18(21(27)28)22(29)30)14-8-4-3-7-13(14)15/h1-8,17-18H,9-10H2,(H,23,24)(H,25,26)(H,27,28)(H,29,30)
SMILES string
OC(=O)C(Cc1c2ccccc2c(CC(C(O)=O)C(O)=O)c3ccccc13)C(O)=O
InChI key
DNUYOWCKBJFOGS-UHFFFAOYSA-N
product line
BioReagent
assay
≥90% (HPCE)
form
powder
solubility
DMSO: soluble
fluorescence
λex 380 nm; λem 407 nm in 0.1 M phosphate pH 7.0
suitability
suitable for fluorescence
Quality Level
Analysis Note
In addition to the emission maximum at 407 nm, there are lower maxima at 431, 457 and 485 nm.
Application
9,10-Anthracenediyl-bis(methylene)dimalonic acid is widely used as a singlet oxygen detector probe. 9,10-Anthracenediyl-bis(methylene)dimalonic acid is suitable for assessing the photodynamic effect of curcumin Vibrio parahaemolyticus, which is a significant cause of bacterial diarrhea.
General description
9,10-Anthracenediyl-bis(methylene)dimalonic acid or ABDA is a singlet oxygen probe. It is highly fluorescent and soluble in water and binds to lipopolysaccharides (LPS) found in the cell membrane. 9,10-Anthracenediyl-bis(methylene)dimalonic acid takes four negative charges upon fully deprotonation in neutral aqueous solutions, stabilizing the ion-pair complex and facilitating selective recognition of LPS over other common ionic species of clinical significance. In addition to the emission maximum at 407 nm, there are lower maxima at 431, 457, and 485 nm.
Other Notes
Reagent for the assay of singlett oxygen; it has better characteristics than 9,10-anthracenediyl-bis-dipropionic acid
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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