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74680

Octaethylene glycol monododecyl ether

Name: Octaethylene glycol monododecyl ether
Brand: SIGMA

BioXtra, ≥98.0% (GC)

Synonym(s):

C₁₂E₈, Dodecyl octaethylene glycol ether, Dodecyloctaglycol, Polyoxyethylene (8) lauryl ether

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About This Item

Linear Formula:

CH₃(CH₂)₁₁(OCH₂CH₂)₈OH

CAS Number:

3055-98-9

Molecular Weight:

538.75

UNSPSC Code:

12161900

NACRES:

NA.25

PubChem Substance ID:

329765791

MDL number:

MFCD00043234

Beilstein/REAXYS Number:

1893466

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Properties

description

non-ionic

Quality Level

200

product line

BioXtra

assay

≥98.0% (GC)

form

solid

mol wt

538.75 g/mol

CMC

0.11

cation traces

Ca: ≤50 mg/kg, Cd: ≤50 mg/kg, Co: ≤50 mg/kg, Cr: ≤50 mg/kg, Cu: ≤50 mg/kg, Fe: ≤50 mg/kg, K: ≤50 mg/kg, Mg: ≤50 mg/kg, Mn: ≤50 mg/kg, Na: ≤50 mg/kg, Ni: ≤50 mg/kg, Pb: ≤50 mg/kg, Zn: ≤50 mg/kg

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3

InChI key

YYELLDKEOUKVIQ-UHFFFAOYSA-N

Description

General description

Octaethylene glycol monododecyl ether is a nonionic detergent.

Application

Detergent used for the study of membrane proteins in a native-like state, e.g. ATPase. Used in a mixed micellar assay for lipoxygenase acting at neutral pH and for functional reconstitution of influenza virus envelopes.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Identification and purification of the reconstitutively active glutamine carrier from rat kidney mitochondria.

C Indiveri et al.

The Biochemical journal, 333 ( Pt 2), 285-290 (1998-07-11)

The glutamine carrier from rat kidney mitochondria, solubilized in dodecyl octaoxyethylene ether (C12E8) and partly purified on hydroxyapatite, was identified and completely purified by Celite chromatography. On SDS/PAGE, the purified glutamine carrier consisted of a single protein band with an

Glycyl betaine is effective in slowing down the irreversible denaturation of a detergent-solubilized membrane protein, sarcoplasmic reticulum Ca2+-ATPase (SERCA1a).

Cédric Montigny et al.

Biochemical and biophysical research communications, 391(1), 1067-1069 (2009-12-17)

Many membrane proteins become labile when they are solubilized by detergent. Here we show that the presence of high concentrations of glycyl betaine stabilizes one of these proteins, the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA1a), solubilized with nonionic detergents like n-dodecyl beta-d-maltopyranoside

[Relationship between activity and tetraprotomeric structure of ion-transporting ATPases].

Kazuhiro Abe et al.

Seikagaku. The Journal of Japanese Biochemical Society, 79(6), 527-534 (2007-08-01)

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Global Trade Item Number

SKU	GTIN
74680-5G	04061833358870
74680-1G	04061826664803
74680-25G	04061833417669