70797
α-Glucosidase from Saccharomyces cerevisiae
lyophilized powder, beige, 4-8 U/mg
Synonym(s):
α-D-Glucosidase, α-D-Glucoside glucohydrolase, Maltase from yeast
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About This Item
CAS Number:
UNSPSC Code:
12352204
EC Number:
232-604-7
MDL number:
Specific activity:
4-8 U/mg
form
lyophilized powder
specific activity
4-8 U/mg
mol wt
Mr ~63000
color
beige
storage temp.
−20°C
Gene Information
bakers yeast ... MAL12(853209), MAL32(852602)
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General description
only partly soluble in water or buffer
Application
For the determination of α-amylase and the synthesis of various 1′-O-sucrose and 1-O-fructose esters
Biochem/physiol Actions
Hydrolysis of terminal, non-reducing 1→4-linked D-glucose residues with release of D-glucose.
Other Notes
1 U corresponds to the amount of enzyme which hydrolyzes 1 μmol p-nitrophenyl-α-D-glucopyranoside per minute at pH 6.8 and 37°C
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Rachel Mata et al.
Journal of natural products, 76(3), 468-483 (2013-02-13)
Type II-diabetes mellitus (TII-DM) has been regarded as one of the most important public health problems in all nations in the 21st century. Although allopathic therapies remain the most important for the initial management of TII-DM, herbal remedies have gained
Shinji Onose et al.
Food chemistry, 138(1), 516-523 (2012-12-26)
1-Deoxynojirimycin (DNJ), a potent α-glycosidase inhibitor, has therapeutic applications in treatments of HIV, Gaucher's disease, and diabetes. DNJ has been extracted from natural sources (mulberry leaves) for therapeutic purposes; however, DNJ ingredients are in limited supply and are costly to
Nicolai Preisler et al.
Molecular genetics and metabolism, 110(3), 287-289 (2013-09-10)
Late-onset Pompe disease is a rare, but potentially treatable metabolic myopathy, and therefore should not be overlooked. However, it is not unusual that patients go undiagnosed for many years. We hypothesized that patients with late-onset Pompe disease may have been
Fei Yang et al.
Food chemistry, 141(4), 3606-3613 (2013-09-03)
Jiaogulan tea has been commercialised globally. This study investigated the chemical components and health properties of a new jiaogulan genotype, tetraploid Gynostemma pentaphyllum. Two new saponins, (23S)-21β-O-methyl-3β,20ξ-dihydroxy-12-oxo-21,23-epoxydammar-24-ene-3-O-[α-L-rhamnopyranosyl(1→2)][β-D-glucopyranosyl(1→3)]-α-L-arabinopyranoside (4) and 23β-H-3β,20ξ-dihydroxy-19-oxo-21,23-epoxydammar-24-ene-3-O-[α-L-rhamnopyranosyl(1→2)][β-D-xylopyranosyl(1→3)]-α-L-arabinopyranoside (5), together with one lactone, 3,5-dihydroxyfuran-2(5H)-one (1), and two flavonoids
Thomas J Conlon et al.
Human gene therapy. Clinical development, 24(3), 127-133 (2013-09-12)
A biodistribution and toxicology study was performed to test the acute toxicities of intradiaphragmatic injection of a recombinant adeno-associated virus (rAAV) 2/1-human acid alpha-Glucosidase (hGAA) driven by a cytomegalovirus (CMV) promoter (rAAV1-CMV-hGAA) in New Zealand white rabbits and in the
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