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Merck
CN

60142

Potassium chloride solution

BioUltra, Molecular Biology, ~1 M in H2O

Synonym(s):

KCl, potassium chloride

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About This Item

Linear Formula:
KCl
CAS Number:
7447-40-7
Molecular Weight:
74.55
UNSPSC Code:
12352302
NACRES:
NA.26
PubChem Substance ID:
57651726
MDL number:
MFCD00011360
Beilstein/REAXYS Number:
1711999
Grade:
Molecular Biology
Form:
liquid (Clear)
Solubility:
water: soluble

Key Documents

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Product Name

Potassium chloride solution, BioUltra, Molecular Biology, ~1 M in H2O

InChI key

WCUXLLCKKVVCTQ-UHFFFAOYSA-M

SMILES string

[Cl-].[K+]

InChI

1S/ClH.K/h1H;/q;+1/p-1

grade

Molecular Biology

product line

BioUltra

form

liquid (Clear)

concentration

~1 M in H2O

impurities

DNases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected
≤0.001% total nitrogen (N)

pH

5.0-8.0 (25 °C, 1 M in H2O)

solubility

water: soluble

density

1.04 g/mL at 20 °C

anion traces

sulfate (SO42-): ≤10 mg/kg

cation traces

Al: ≤1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.02
λ: 280 nm Amax: 0.01

Quality Level

200

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Application

Potassium chloride solution has been used as a component of:
  • multiple annealing and looping based amplification cycles (MALBAC) lysis buffer to digest proteins for single-cell multiomics sequencing
  • single-cell tagged reverse transcription (STRT) buffer, and STRT-RT buffer for single-cell RNA-sequencing
  • phosphate buffer saline (PBS) to wash transfected cells

General description

Potassium is an intracellular cation with just 2% of total body K+ inhabiting the extracellular fluid. The distribution of K+ between the intracellular and extracellular space is analyzed by the action of several transport pathways like Na+-K+-ATPase, the Na+-K+-2Cl-cotransporter NKCC1, the four KCCs, and a plethora of K+ channels. Also, skeletal muscle comprises almost 75% of total body potassium and elicits considerable influence on extracellular K+. Potassium chloride is consumed orally to prevent or correct potassium depletion caused by diuretic use or other conditions. It is used as a food supplement and salt substitute.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7107
BCCN2915
BCCL2363
BCCL7719
BCCM4106

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Transport of Sodium, Chloride, and Potassium
Brenner and Rector's The Kidney E-book (2019)
Meyler's Side Effects of Drugs (2016)
Takanobu Kato et al.
Nature protocols, 1(5), 2334-2339 (2007-04-05)
Hepatitis C virus (HCV) infection causes chronic liver disease and is a worldwide health problem. Despite ever-increasing demand for knowledge on viral replication and pathogenesis, detailed analysis has been hampered by a lack of efficient viral culture systems. We isolated
Yuanyuan Qu et al.
Nucleic acids research, 41(10), 5263-5272 (2013-04-13)
Bacterial nucleoid-associated proteins, such as H-NS-like proteins in Enterobacteriaceae, are abundant DNA-binding proteins that function in chromosomal DNA organization and gene transcription regulation. The Mycobacterium tuberculosis Lsr2 protein has been proposed to be the first identified H-NS analogue in Gram-positive
Calista K L Ng et al.
Human molecular genetics, 24(11), 3163-3171 (2015-02-26)
mRNA decay is an essential and active process that allows cells to continuously adapt gene expression to internal and environmental cues. There are two mRNA degradation pathways: 3' to 5' and 5' to 3'. The DCPS protein is the scavenger
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