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59769

Sigma-Aldrich

Micro particles based on polystyrene

size: 500 nm

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Synonym(s):
Latex beads from PS
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32

Quality Level

form

aqueous suspension

concentration

10% (solids)

particle size

500 nm

density

1.05 g/cm3

storage temp.

2-8°C

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General description

Micro Particles or Latex Beads, commonly known as polystyrene microparticles, are negatively charged colloidal particles. The microparticles are produced through a polymerization reaction of styrene under controlled conditions. The conducive environment of the reaction induces spontaneous coalescent bead formation. Micro Particles or Latex beads are supplied in aqueous solutions composed of polymer particles with water. Polystyrene′s refractive index at 589 nm is 1.5905 and 1.602 at 486 nm.

Application

Micro Particles or Latex Beads is used for a wide variety of applications like:

  • Electron Microscopy.
  • Cell Counter Calibration.
  • Immunodiagnostics, especially for latex agglutination tests, and
  • Phagocytosis Research.

Analysis Note

For every lot exact values of particle size and standard deviation are determined with an accuracy of 0.01 μm using a Coulter Multisizer.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Elizabeth M Walker et al.
Journal of colloid and interface science, 363(1), 307-313 (2011-08-16)
We have studied polydimethylsiloxane (PDMS)-in-1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF(6)]) Pickering emulsions stabilized by polystyrene microparticles with different surface chemistry. Surprisingly, in contrast to the consensus originating from oil/water Pickering emulsions in which the solid particles equilibrate at the oil-water droplet interfaces and
Sensitive Mie scattering immunoagglutination assay of porcine reproductive and respiratory syndrome virus (PRRSV) from lung tissue samples in a microfluidic chip.
Song JY, Lee CH, Choi EJ, Kim K, et al.
J. Virol. Methods, 178, 31-38 (2011)
Fiona A Sharp et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(3), 870-875 (2009-01-14)
Many currently used and candidate vaccine adjuvants are particulate in nature, but their mechanism of action is not well understood. Here, we show that particulate adjuvants, including biodegradable poly(lactide-co-glycolide) (PLG) and polystyrene microparticles, dramatically enhance secretion of interleukin-1beta (IL-1beta) by
Shunmugaperumal Tamilvanan et al.
PDA journal of pharmaceutical science and technology, 62(3), 177-190 (2008-07-30)
The objective of this study is to select a multiple-unit sustained-release formulation and to compare it with both commercial immediate and single unit sustained-release capsules and also to determine whether an in vitro-in vivo correlation exists for single- and multiple-

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