55345
N-Methyl-L-threonine
≥98% (TLC)
Synonym(s):
(2S,3R)-3-Hydroxy-2-(methylamino)butyric acid, N-Me-Thr-OH
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C5H11NO3
CAS Number:
Molecular Weight:
133.15
PubChem Substance ID:
UNSPSC Code:
12352202
Beilstein/REAXYS Number:
1722279
MDL number:
SMILES string
CN[C@@H]([C@@H](C)O)C(O)=O
InChI
1S/C5H11NO3/c1-3(7)4(6-2)5(8)9/h3-4,6-7H,1-2H3,(H,8,9)/t3-,4+/m1/s1
InChI key
CCAIIPMIAFGKSI-DMTCNVIQSA-N
assay
≥98% (TLC)
form
powder
optical activity
[α]/D -24.0±1.0°, c = 1 in 1 M HCl
composition
carbon, 44.2-46.0% , nitrogen, 10.3-10.8%
color
white
storage temp.
2-8°C
Biochem/physiol Actions
N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service