53319
L-Histidine
≥99.5% (NT), BioUltra
Synonym(s):
(S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
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About This Item
Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
Molecular Weight:
155.15
Beilstein:
84088
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
Recommended Products
Product Name
L-Histidine, BioUltra, ≥99.5% (NT)
product line
BioUltra
Assay
≥99.5% (NT)
form
powder or crystals
optical activity
[α]20/D −39±1°, c = 2% in H2O
impurities
insoluble matter, passes filter test
≤0.5% foreign amino acids
ign. residue
≤0.1% (as SO4)
loss
≤0.5% loss on drying, 110 °C
color
white
pH
7.0-8.0 (25 °C, 0.1 M in H2O)
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Application
L-Histidine has been used for characterization of ZnO nanorod in an attempt to develop a technique for the ultra-low level detection of l-histidine.
Biochem/physiol Actions
L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.
Precursor of histamine by action of histidine decarboxylase.
Other Notes
Amino acid spacing in isotachophoresis on polyacrylamide gels - a critical evaluation; Prevents circular DNA strand cleavage in a xanthine-xanthine oxidase system; Growth requirement of various microorganisms.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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K Brawn et al.
Acta physiologica Scandinavica. Supplementum, 492, 9-18 (1980-01-01)
An enzymic flux of O2- and H2O2 caused strand breaks in the supercoiled covalently closed circular Col El plasmid. Subnanomolar levels of superoxide levels of superoxide dismutase or of catalase prevented this attack on DNA, signifying that both O2- and
CRC Handbook of Microbiology, 4, 1-1 (1974)
Ultra-Low Level Detection of L-Histidine Using Solution-Processed ZnO Nanorod on Flexible Substrate.
Sasmal M
IEEE Transactions on Nanobioscience, 14(6), 634-640 (2015)
Amino acid spacing in isotachophoresi; on polyacrylamide gel: a critical evaluation.
N Y Nguyen et al.
Analytical biochemistry, 94(1), 202-210 (1979-04-01)
Shweta Singh et al.
Microbial cell factories, 7, 28-28 (2008-10-14)
The large-scale production of G-protein coupled receptors (GPCRs) for functional and structural studies remains a challenge. Recent successes have been made in the expression of a range of GPCRs using Pichia pastoris as an expression host. P. pastoris has a
Chromatograms
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