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Merck
CN

50839

Catalpol

≥96% (HPLC)

Synonym(s):

(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside, Catalpinoside, De(p-hydroxybenzoyl)catalposide

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About This Item

Empirical Formula (Hill Notation):
C15H22O10
CAS Number:
2415-24-9
Molecular Weight:
362.33
NACRES:
NA.25
PubChem Substance ID:
329757639
UNSPSC Code:
12352211
EC Number:
219-324-0
MDL number:
MFCD11111524

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Product Name

Catalpol, ≥96% (HPLC)

InChI key

LHDWRKICQLTVDL-PZYDOOQISA-N

InChI

1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1

SMILES string

OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](O)[C@@H]4O[C@]4(CO)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O

assay

≥96% (HPLC)

storage temp.

−20°C

Quality Level

100

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Biochem/physiol Actions

The primary function is to stimulate the production of adrenal cortical hormones, which increases the production of sex hormones. Catalpol also exhibits anti-inflammatory activity and has shown to increase the production of androgens yielded by the adrenal gland, which can lead to increases in muscle mass.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF4176V
BCCH6295
BCCF1851
BCBX4606
BCBV4769

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Lijuan Deng et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(10), 1472-1476 (2012-08-07)
To study the effect of catalpol and puerarin freeze-dried powder for injection (CPFPI), a new compound traditional Chinese medicine (TCM) preparation, on coagulability, hemorheology and NO in rats with qi-deficiency and blood-stasis syndrome. The model of rats with qi-deficiency and
Huifeng Zhu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(23), 2983-2986 (2010-03-13)
Catalpol is a effective components of rehmannia root, it have many pharmacological actions, such as anti-brain ischemia, anti-senile dementia, promoting neuro-remodeling and reducing capillary permeability and so on.
D T Davitashvili et al.
Georgian medical news, (177)(177), 73-77 (2010-01-22)
The oxidative stress-induced changes and feasibility of prevention of these changes with an aid of vitamines E and C were investigated in cultured brain cortex of the newborn albino rats. Modeling the oxidative stress was achieved with addition of H(2)O(2)
Kristen M Michaud et al.
Environmental entomology, 48(3), 685-690 (2019-03-12)
Bumble bee pollinators can be exposed to pathogens when foraging on flowers previously visited by infected individuals. Infectious cells may be deposited in floral nectar, providing a site for pathogens to interact with nectar secondary compounds prior to infecting bees.
Ziqiang Zhang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(15), 1955-1958 (2009-11-10)
To study the protective effects of catalpol against H2O2-induced oxidative damage in astrocytes. Astrocytes were pretreated with 1, 10, 100 micromol x L(-1) catalpol and then exposed to H2O2. Effects of catalpol on cell morphous were observed by inverted microscope.
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