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50200

Sigma-Aldrich

Gly-Gly

≥99.0% (NT), suitable for ligand binding assays, BioXtra

Synonym(s):

Diglycine, Glycyl-glycine

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100 μL
CN¥5,074.24

CN¥5,074.24

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100 μL
CN¥5,074.24

About This Item

Linear Formula:
NH2CH2CONHCH2COOH
CAS Number:
556-50-3
Molecular Weight:
132.12
Beilstein:
1765223
EC Number:
209-127-8
MDL number:
MFCD00008130
UNSPSC Code:
12161700
PubChem Substance ID:
329757576
NACRES:
NA.25

CN¥5,074.24

Please contact Customer Service for Availability
Request a Bulk Order

Product Name

Gly-Gly, BioXtra, ≥99.0% (NT)

product line

BioXtra

Quality Level

200

Assay

≥99.0% (NT)

form

powder

technique(s)

ligand binding assay: suitable

ign. residue

≤0.1% (as SO4)

loss

≤1% loss on drying, 110 °C

color

white

useful pH range

7.5-8.9

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多西环素 单盐酸半乙醇半水合物 Pharmaceutical Secondary Standard; Certified Reference Material

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多西环素 单盐酸半乙醇半水合物 Suitable for Cell Culture

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盐酸强力霉素 A commonly-used broad-spectrum antibiotic.

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application(s)

clinical testing

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

format

neat

format

neat

format

-

format

-

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

100

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

grade

-

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

Biochem/physiol Actions

Glycine is a non-essential amino acid.[1] Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors.[2] Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.[1] Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.[3]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCN1637
    BCCM9603
    BCCM4613
    BCCL7756
    BCCK4178

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    Glycine and diglycine as possible catalytic factors in the prebiotic evolution of peptides.
    Plankensteiner K
    Origins of Life and Evolution of the Biosphere : the Journal of the International Society For the Study of the Origin of Life, 32(3), 225-236 (2002)
    Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
    Mohit Jain
    Science, 336(6084), 1040-1044 (2012)
    Lasse Jenner et al.
    Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3812-3816 (2013-02-23)
    Here we present an X-ray crystallography structure of the clinically relevant tigecycline antibiotic bound to the 70S ribosome. Our structural and biochemical analysis indicate that the enhanced potency of tigecycline results from a stacking interaction with nucleobase C1054 within the
    Namrata D Udeshi et al.
    Molecular & cellular proteomics : MCP, 12(3), 825-831 (2012-12-26)
    Detection of endogenous ubiquitination sites by mass spectrometry has dramatically improved with the commercialization of anti-di-glycine remnant (K-ε-GG) antibodies. Here, we describe a number of improvements to the K-ε-GG enrichment workflow, including optimized antibody and peptide input requirements, antibody cross-linking
    P B Armentrout et al.
    Journal of the American Society for Mass Spectrometry, 23(4), 632-643 (2011-09-29)
    We present a full molecular description of fragmentation reactions of protonated diglycine (H(+)GG) by studying their collision-induced dissociation (CID) with Xe using a guided ion beam tandem mass spectrometer (GIBMS). Analysis of the kinetic energy-dependent CID cross sections provides the
    View All Related Papers

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