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Merck
CN

49225

α-D-Glucose 1,6-bisphosphate potassium salt hydrate

≥99.0% (TLC)

Synonym(s):

α-D-Glucose 1,6-diphosphate potassium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C6H10K4O12P2 · xH2O
CAS Number:
91183-87-8
Molecular Weight:
492.48 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
57651179
UNSPSC Code:
12352201
MDL number:
MFCD00150469

Key Documents

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Product Name

α-D-Glucose 1,6-bisphosphate potassium salt hydrate, ≥99.0% (TLC)

InChI key

OVRXVCAVDXBPQT-QMKHLHGBSA-J

SMILES string

[K+].[K+].[K+].[K+].O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@H](OP([O-])([O-])=O)[C@@H]1O

InChI

1S/C6H14O12P2.4K/c7-3-2(1-16-19(10,11)12)17-6(5(9)4(3)8)18-20(13,14)15;;;;/h2-9H,1H2,(H2,10,11,12)(H2,13,14,15);;;;/q;4*+1/p-4/t2-,3-,4+,5-,6-;;;;/m1..../s1

assay

≥99.0% (TLC)

form

solid

impurities

≤15% water

color

white

solubility

H2O: 50 mg/mL, clear, colorless

storage temp.

−20°C

Quality Level

200

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Related Categories

Application

α-D-Glucose 1,6-bisphosphate is used in the identification, differentiation and characterization of α-phosphoglucomutase(s), β-phosphoglucomutase(s) and α- and β-hexoglucomutase(s).

Biochem/physiol Actions

Metabolite formed via the activity of Glucose-1,6-biphosphate synthase. Glucose-1,6-biphosphate (G-1,6-BP) acts as an inhibitor of hexokinase function and an activator of phosphofructokinase-1 and pyruvate kinase. G-1,6-BP also acts as a coenzyme for phosphoglucomutate and a cofactor for phosphopentomutase.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ0154
BCCF4532
BCCF1723
BCBW0814
BCBT5278

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Jessica P Lao et al.
G3 (Bethesda, Md.), 9(2), 413-423 (2018-12-12)
Phosphomannomutase 2 Deficiency (PMM2-CDG) is the most common monogenic congenital disorder of glycosylation (CDG) affecting at least 800 patients globally. PMM2 orthologs are present in model organisms, including the budding yeast Saccharomyces cerevisiae gene SEC53 Here we describe conserved genotype-phenotype

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