Skip to Content
Merck
CN
All Photos(3)

Key Documents

Safety Information

446R-1

Sigma-Aldrich

Steroidogenic Acute Regulatory Protein (STAR) (EP226) Rabbit Monoclonal Primary Antibody

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

UNSPSC Code:
12352203

biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

EP226, monoclonal

description

For In Vitro Diagnostic Use in Select Regions

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (446R-14)
vial of 0.1 mL concentrate Research Use Only (446R-14-RUO)
vial of 0.5 mL concentrate (446R-15)
vial of 1.0 mL concentrate (446R-16)
vial of 1.0 mL concentrate Research Use Only (446R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (446R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (446R-17)
vial of 7.0 mL pre-dilute ready-to-use (446R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (446R-18-RUO)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

isotype

IgG

control

adrenal cortex

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... STAR(6770)

General description

Steroidogenic Acute Regulatory Protein (STAR) is a sterol transfer protein that is critical for steroidegenesis. Steroidegenesis is the process where steroid hormones are made within specialized cells. STAR controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. Immunohistochemically, STAR is a cytoplasmic marker that is generally localized in the normal and neoplastic cells of steroid hormone producing tissues such as testis and adrenal gland. Due to their low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, this antibody may assist in differentiating sex cord stromal tumors, seminomas and embryonal carcinomas.

Quality


IVD
IVD
IVD
RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S E Pollack et al.
The Journal of clinical endocrinology and metabolism, 82(12), 4243-4251 (1997-12-17)
The rate-limiting step in steroid hormone production in the adrenal cortex and gonads, the translocation of cholesterol from the outer to the inner mitochondrial membranes, is mediated by the steroidogenic acute regulatory protein (StAR). Heretofore, the localization of StAR in
C B Kallen et al.
The Journal of biological chemistry, 273(41), 26285-26288 (1998-10-03)
Steroidogenic acute regulatory protein (StAR) plays a critical role in steroidogenesis by enhancing the delivery of substrate cholesterol from the outer mitochondrial membrane to the cholesterol side chain cleavage enzyme system on the inner membrane. A recombinant StAR protein lacking
Chih-Hsien Chin et al.
The Chinese journal of physiology, 51(1), 54-61 (2008-06-17)
We report production of a polyclonal antibody against the StAR (steroidogenic acute regulatory) protein of steroidogenic cells and immunohistochemistry (IHC) staining of bovine adrenal gland tissue available in paraffin block. The epitope-specific polyclonal antibody was produced in a rabbit immunized

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service