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Safety Information

41563

Sigma-Aldrich

Manganese Peroxidase from Nematoloma frowardii

≥4.2 U/mg

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About This Item

CAS Number:
Enzyme Commission number:
MDL number:
UNSPSC Code:
12352204

biological source

fungus (Nematoloma frowardii)

Quality Level

form

powder

specific activity

≥4.2 U/mg

storage temp.

−20°C

Application

Manganese peroxidase (MnP) is used to oxidize Mn2+ to Mn3+ in the presence of hydrogen peroxide. It is used for the biodegreadation of macromolecular substances such as lignin and humic substances .

Biochem/physiol Actions

Manganese peroxidase (MnP) is a hemecontaining glycoprotein that is produced by ligninolytic basidiomycetes. It requires hydrogen peroxide as an oxidant. MnP oxidizes Mn2+ to Mn3+. Mn3+ oxidizes phenolic rings to phenoxy radicals which results in the decomposition of various compounds .

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Unit Definition

1 U corresponds to the amount of enzyme which oxidizes 1 μmol Mn2+ to Mn3+ per minute at pH 4.5 and 25°C (in the presence of H2O2).

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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M Hofrichter et al.
Applied and environmental microbiology, 64(2), 399-404 (2005-12-14)
The direct involvement of manganese peroxidase (MnP) in the mineralization of natural and xenobiotic compounds was evaluated. A broad spectrum of aromatic substances were partially mineralized by the MnP system of the white rot fungus Nematoloma frowardii. The cell-free MnP
Dong-Soo Moon et al.
Applied biochemistry and biotechnology, 168(3), 542-549 (2012-07-14)
Alkylphenols are common endocrine disrupters that are produced from the degradation of widely used surfactants. Since they cause various harmful effects on aquatic life and in humans, they should be removed from the environments being contaminated. White rot fungus Irpex
Kannan Pakshirajan et al.
Journal of environmental management, 101, 118-123 (2012-03-13)
Coloured industry wastewaters often contain dyes and other toxic ingredients, and, therefore, pose serious threat to the receiving environment. Among the available methods the eco-friendly biological method has gained maximum attention due to its many advantages over the traditional methods.
Alexander N Kapich et al.
Enzyme and microbial technology, 49(1), 25-29 (2011-11-25)
The peroxidation of C18 unsaturated fatty acids by fungal manganese peroxidase (MnP)/Mn(II) and by chelated Mn(III) was studied with application of three different methods: by monitoring oxygen consumption, by measuring conjugated dienes and by thiobarbituric acid-reactive substances (TBARS) formation. All
Tomer M Salame et al.
Applied and environmental microbiology, 78(15), 5341-5352 (2012-05-29)
Pleurotus ostreatus (the oyster mushroom) and other white rot filamentous basidiomycetes are key players in the global carbon cycle. P. ostreatus is also a commercially important edible fungus with medicinal properties and is important for biotechnological and environmental applications. Efficient

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