41486
L-Histidinol phosphate lithium salt
≥95% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C6H12N3O4P · xLi+
Molecular Weight:
221.15 (free acid basis)
UNSPSC Code:
12352202
assay
≥95% (HPLC)
storage temp.
−20°C
Biochem/physiol Actions
Central metabolite in the histidine biosynthesis pathway of bacteria, yeasts and plants, substrate for histidinolphosphate amino-transferase, structure of covalent complex with histidinol-phosphate aminotransferase. Substrate for L-histidinol phosphate phosphatase in the penultimaze step of L-histidine biosynthesis.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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J Sivaraman et al.
Journal of molecular biology, 311(4), 761-776 (2001-08-24)
The biosynthesis of histidine is a central metabolic process in organisms ranging from bacteria to yeast and plants. The seventh step in the synthesis of histidine within eubacteria is carried out by a pyridoxal-5'-phosphate (PLP)-dependent l-histidinol phosphate aminotransferase (HisC, EC
Swapnil V Ghodge et al.
Biochemistry, 52(6), 1101-1112 (2013-01-19)
L-Histidinol phosphate phosphatase (HPP) catalyzes the hydrolysis of L-histidinol phosphate to L-histidinol and inorganic phosphate, the penultimate step in the biosynthesis of L-histidine. HPP from the polymerase and histidinol phosphatase (PHP) family of proteins possesses a trinuclear active site and
Francisco J Fernandez et al.
The Journal of biological chemistry, 279(20), 21478-21488 (2004-03-10)
In histidine biosynthesis, histidinol-phosphate aminotransferase catalyzes the transfer of the amino group from glutamate to imidazole acetol-phosphate producing 2-oxoglutarate and histidinol phosphate. In some organisms such as the hyperthermophile Thermotoga maritima, specific tyrosine and aromatic amino acid transaminases have not
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