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Sigma-Aldrich

N,N-Dimethyldodecylamine N-oxide solution

~30% in H2O

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Synonym(s):
DDAO, LDAO, Lauryldimethylamine N-oxide
Empirical Formula (Hill Notation):
C14H31NO
CAS Number:
1643-20-5
Molecular Weight:
229.40
Beilstein:
1769927
MDL number:
MFCD00002049
UNSPSC Code:
12352119
PubChem Substance ID:
57649948
NACRES:
NA.25

description

non-ionic

Quality Level

200

form

liquid

mol wt

229.40 g/mol

concentration

~30% in H2O

technique(s)

protein quantification: suitable

refractive index

n20/D 1.378

density

0.982 g/mL at 20 °C

SMILES string

CCCCCCCCCCCC[N+](C)([O-])C

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

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General description

N,N-Dimethyldodecylamine N-oxide (DDAO), an amphoteric surfactant, is nonionic at high pH. The surfactant headgroup of amphoteric surfactants may carry positive and negative charges as the net charge is pH sensitive.

Application

N,N-Dimethyldodecylamine N-oxide solution has been used:
  • to examine the individual components of solvable for the extraction of few-layer graphene (FLG)and graphene oxide (GO) from complex organic matrices
  • as a component of wash buffer, elution buffer, and anion loading buffer for the purification of the double mutant reaction centers (DM RCs)
  • in the extraction of bilirubin and biliverdin by high-performance liquid chromatography (HPLC)

Biochem/physiol Actions

N,N-Dimethyldodecylamine N-oxide (DDAO) is preferred for protein studies. It is also frequently utilized for the extraction of membrane proteins.

Features and Benefits

  • Suitable for protein quantification

Pictograms

CorrosionEnvironment
GHS05,GHS09

Signal Word

Danger

Hazard Statements

H315,H318,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Karl B McCann et al.
Biologicals : journal of the International Association of Biological Standardization, 37(1), 32-36 (2008-10-25)
Human serum albumin is a well tolerated therapeutic for the treatment of hypovolemia. Despite all commercial human albumin preparations being derived from plasma, these products can have a highly variable colour. Albumin samples derived from ethanol precipitation and chromatographic fractionation
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The formation of defined surfaces consisting of photosynthetic reaction centers (RCs) in biohybrid solar cells is challenging. Here, we start with the production of engineered RCs for oriented binding. RCs are deposited onto gold electrodes, and 6-mercapto-1-hexanol (MCH) is used
David S White et al.
eLife, 9 (2020-04-09)
Single-molecule approaches provide enormous insight into the dynamics of biomolecules, but adequately sampling distributions of states and events often requires extensive sampling. Although emerging experimental techniques can generate such large datasets, existing analysis tools are not suitable to process the
Thomas Kupke et al.
Communications biology, 3(1), 73-73 (2020-02-16)
Transmembrane signaling proteins play a crucial role in the transduction of information across cell membranes. One function of regulated intramembrane proteolysis (RIP) is the release of signaling factors from transmembrane proteins. To study the role of transmembrane domains (TMDs) in modulating
Aleksandr A Goncharenko et al.
Molecules (Basel, Switzerland), 25(17) (2020-08-23)
The design of cargo carriers with high biocompatibility, unique morphological characteristics, and capability of strong bonding of fluorescent dye is highly important for the development of a platform for smart imaging and diagnostics. In this paper, BODIPY-doped silica nanoparticles were
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