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Sigma-Aldrich

Lycopene, Redivivo™

10% FS, ~10% in corn oil, ≥95.0% (sum of isomers)

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Synonym(s):
Lycopene, dispersion
Empirical Formula (Hill Notation):
C40H56
CAS Number:
502-65-8
Molecular Weight:
536.87
EC Number:
232-281-2
MDL number:
MFCD00017350
UNSPSC Code:
12352200
PubChem Substance ID:
329755000
NACRES:
NA.47

Quality Level

100

Assay

≥95.0% (sum of isomers)

contains

≤2.5% α-Tocopherol as stabilizer

concentration

~10% in corn oil

storage temp.

2-8°C

SMILES string

C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C

InChI

1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+

InChI key

OAIJSZIZWZSQBC-GYZMGTAESA-N

Related Categories

Biochem/physiol Actions

Lycopene is a red phytochemical pigment found in tomatoes. The main carotenoid in human plasma, it is a highly potent antioxidant, the most efficient biological quencher of singlet oxygen, associated with decreased risk of cancer and cardiovascular diseases. Lycopene enhances gap junction communication between cells via upregulation of connexin 43 and reduces profileration of cancer cells in culture. Inhibits cholesterol synthesis and enhances low-density lipoprotein degradation. Lycopene in skin sacrificially protects against UV-induced degradation of β-carotene.

Other Notes

REDIVIVO is a non-toxic, stable formulation of lycopene (10% dispersion in corn oil) that offers convenient handling and is dust-free.

Legal Information

Redivivo is a trademark of DSM Nutritional Products AG

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P280 - P302 + P352

Hazard Classifications

Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wilhelm Stahl et al.
Skin pharmacology and applied skin physiology, 15(5), 291-296 (2002-09-20)
Upon exposure to UV light photooxidative reactions are initiated which are damaging to biomolecules and affect the integrity of cells and tissues. Photooxidative damage plays a role in pathological processes and is involved in the development of disorders affecting the
P Di Mascio et al.
Archives of biochemistry and biophysics, 274(2), 532-538 (1989-11-01)
Lycopene, a biologically occurring carotenoid, exhibits the highest physical quenching rate constant with singlet oxygen (kq = 31 X 10(9) M-1 s-1), and its plasma level is slightly higher than that of beta-carotene (kq = 14 X 10(9) M-1 s-1).
Dragan Ilic et al.
The Cochrane database of systematic reviews, (11)(11), CD008007-CD008007 (2011-11-11)
Prostate cancer is a common cause of death in developed countries, yet the benefits of screening for prostate cancer still remain controversial. A prostate-specific antigen (PSA) test result greater than 4 ng/mL (nanograms/millilitre) has commonly been used as the cut-off
Dragan Ilic et al.
Maturitas, 72(4), 269-276 (2012-05-29)
Prostate cancer is a leading cancer affecting men worldwide. Benign prostatic hyperplasia (BPH) is a common disease of the prostate affecting men as they age, and a risk factor for developing prostate cancer. Lycopene is a member of the carotenoid
J D Ribaya-Mercado et al.
The Journal of nutrition, 125(7), 1854-1859 (1995-07-01)
This placebo-controlled study examined in healthy women the effects of ingestion of a single large dose of beta-carotene (120 mg) on the concentrations of beta-carotene and lycopene in plasma and skin, and the effects of UV light exposure on the
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