33484
1,8-Diazafluoren-9-one
Synonym(s):
Cyclopenta[1,2-b:4,3-b’]dipyridin-9-one
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About This Item
Empirical Formula (Hill Notation):
C11H6N2O
CAS Number:
Molecular Weight:
182.18
Beilstein:
134499
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.32
Quality Level
mp
229-233 °C
solubility
acetic acid: 10 mg/mL, clear
fluorescence
λex 470 nm; λem 570 nm
storage temp.
2-8°C
SMILES string
O=C1c2ncccc2-c3cccnc13
InChI
1S/C11H6N2O/c14-11-9-7(3-1-5-12-9)8-4-2-6-13-10(8)11/h1-6H
InChI key
FOSUVSBKUIWVKI-UHFFFAOYSA-N
Application
1,8-Diazafluoren-9-one (DFO) is used in forensic science to detect latent fingerprints on paper and other materials. DFO forms highly fluorescent derivatives with amino acids (excitation ~470 nm; emission ~570 nm).
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Reagent forming highly fluorescent derivatives with amino acids (excitation ~470 nm; emission ~570 nm). Used for the detection of latent fingerprints on paper with high sensitivity.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Certificates of Analysis (COA)
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Aneta Lewkowicz et al.
Materials (Basel, Switzerland), 13(13) (2020-07-10)
The investigation of innovative label-free α-amino acids detection methods represents a crucial step for the early diagnosis of several diseases. While 1,8-diazafluoren-9-one (DFO) is known in forensic application because of the fluorescent products by reacting with the amino acids present
C.A. Pounds et al.
Journal of Forensic Sciences, 35, 169-169 (1990)
D Wilkinson
Forensic science international, 109(2), 87-103 (2000-03-08)
This paper describes the study of the reaction between 1, 8-diazafluoren-9-one (DFO) with the amino acid L-alanine in methyl alcohol. Particular interest was paid to the possible role of the solvent which appears to react with the DFO to form
Danna E Bicknell et al.
Journal of forensic sciences, 53(5), 1108-1116 (2008-07-22)
1,2-Indanedione belongs to a class of compounds which have demonstrated great potential in the processing of latent prints, particularly in the area of fluorescence. However, variability in results achieved worldwide has precluded it from being used extensively. In order to
Kelly Mayse et al.
Science & justice : journal of the Forensic Science Society, 59(3), 349-358 (2019-05-06)
A study into the modification of 1,8-diazafluoren-9-one (DFO) formulations by the additions of metal salts into the working solution is reported. Similar additions have been found to increase the fluorescence of marks developed using other amino acid reagents including 1,2-indandione
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