33484
1,8-Diazafluoren-9-one
Synonym(s):
Cyclopenta[1,2-b:4,3-b’]dipyridin-9-one
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About This Item
Empirical Formula (Hill Notation):
C11H6N2O
CAS Number:
Molecular Weight:
182.18
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
134499
InChI
1S/C11H6N2O/c14-11-9-7(3-1-5-12-9)8-4-2-6-13-10(8)11/h1-6H
SMILES string
O=C1c2ncccc2-c3cccnc13
InChI key
FOSUVSBKUIWVKI-UHFFFAOYSA-N
mp
229-233 °C
solubility
acetic acid: 10 mg/mL, clear
fluorescence
λex 470 nm; λem 570 nm
storage temp.
2-8°C
Quality Level
Application
1,8-Diazafluoren-9-one (DFO) is used in forensic science to detect latent fingerprints on paper and other materials. DFO forms highly fluorescent derivatives with amino acids (excitation ~470 nm; emission ~570 nm).
Other Notes
Reagent forming highly fluorescent derivatives with amino acids (excitation ~470 nm; emission ~570 nm). Used for the detection of latent fingerprints on paper with high sensitivity.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Danna E Bicknell et al.
Journal of forensic sciences, 53(5), 1108-1116 (2008-07-22)
1,2-Indanedione belongs to a class of compounds which have demonstrated great potential in the processing of latent prints, particularly in the area of fluorescence. However, variability in results achieved worldwide has precluded it from being used extensively. In order to
D Wilkinson
Forensic science international, 109(2), 87-103 (2000-03-08)
This paper describes the study of the reaction between 1, 8-diazafluoren-9-one (DFO) with the amino acid L-alanine in methyl alcohol. Particular interest was paid to the possible role of the solvent which appears to react with the DFO to form
C.A. Pounds et al.
Journal of Forensic Sciences, 35, 169-169 (1990)
Aneta Lewkowicz et al.
Materials (Basel, Switzerland), 13(13) (2020-07-10)
The investigation of innovative label-free α-amino acids detection methods represents a crucial step for the early diagnosis of several diseases. While 1,8-diazafluoren-9-one (DFO) is known in forensic application because of the fluorescent products by reacting with the amino acids present
Kelly Mayse et al.
Science & justice : journal of the Forensic Science Society, 59(3), 349-358 (2019-05-06)
A study into the modification of 1,8-diazafluoren-9-one (DFO) formulations by the additions of metal salts into the working solution is reported. Similar additions have been found to increase the fluorescence of marks developed using other amino acid reagents including 1,2-indandione
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