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332A-1

Sigma-Aldrich

Somatostatin Rabbit Polyclonal Antibody

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About This Item

UNSPSC Code:
12352202

biological source

rabbit

Quality Level

100
500

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (332A-14)
vial of 0.5 mL concentrate (332A-15)
bottle of 1.0 mL predilute (332A-17)
vial of 1.0 mL concentrate (332A-16)
bottle of 7.0 mL predilute (332A-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:1000

control

pancreas

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... SST(6750)

General description

Anti-Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells identification can be used to identify hyperplasia of the pancreatic islets as well as islet cell tumors such as somatostatinomas. Somatostain can also be found in gastrointestinal and bronchopulmonary endocrine cells, thymic endocrine cells, and thyroid C cells. Somatostatin suppresses gastric acid secretion, gallbladder contractions, and pancreatic enzyme secretion.

Quality


IVD
IVD
IVD
RUO

Linkage

Somatostatin Positive Control Slides , Product No. 332S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
0000047546
0000047545
0000045313
0000045314
0000045315

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G Somers et al.
Gastroenterology, 85(5), 1192-1198 (1983-11-01)
A duodenal somatostatinoma is described in a patient suffering from a tumoral obstruction of the bile duct. The diagnosis was based upon histologic and immunocytochemical characterization of tumoral fragments and later confirmed by immunochemical analysis of liver metastases. Basal peripheral
G Fried et al.
Cancer, 74(1), 142-151 (1994-07-01)
A case of a renin-producing paraganglioma of adrenal origin with metastases to the retroperitoneal area, paravaginal area, and the ovary is reported with immunohistochemical findings indicating expression of multiple neuropeptide immunoreactivities. The patient was 23 years old at the time
M Quartu et al.
Journal of chemical neuroanatomy, 6(2), 79-99 (1993-03-01)
The occurrence of vasoactive intestinal polypeptide (VIP), peptide histidine-isoleucine (PHI), calcitonin gene-related peptide (CGRP), substance P (SP), somatostatin (SOM), galanin (GAL) and enkephalins (ENK) is studied in the human celiac/superior mesenteric ganglionic complex of pre- and full-term newborns, and adult
G Chejfec et al.
Ultrastructural pathology, 16(5), 537-545 (1992-09-01)
Upper gastrointestinal tract neuroendocrine tumors producing predominantly somatostatin have thus far been described only in the duodenum; their characteristic features include the frequent presence of psammoma bodies (psammomatous somatostinomas), and the association with von Recklinghausen's neurofibromatosis. Gastric neuroendocrine tumors, on
H L Waldum et al.
Cancer detection and prevention, 18(6), 431-436 (1994-01-01)
Previously, we have shown that a significant proportion of human gastric carcinomas of the diffuse type may be neuroendocrine tumors derived from the enterochromaffinlike (ECL) cell. The growth of the ECL cell is specifically regulated by gastrin, suggesting an important
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