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Merck
CN

332A-1

Somatostatin Rabbit Polyclonal Antibody

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About This Item

UNSPSC Code:
12352202
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p)
Citations:
10

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (332A-14), vial of 0.5 mL concentrate (332A-15), bottle of 1.0 mL predilute (332A-17), vial of 1.0 mL concentrate (332A-16), bottle of 7.0 mL predilute (332A-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200-1:1000

control

pancreas

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Quality Level

100, 500

Gene Information

human ... SST(6750)

General description

Anti-Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells identification can be used to identify hyperplasia of the pancreatic islets as well as islet cell tumors such as somatostatinomas. Somatostain can also be found in gastrointestinal and bronchopulmonary endocrine cells, thymic endocrine cells, and thyroid C cells. Somatostatin suppresses gastric acid secretion, gallbladder contractions, and pancreatic enzyme secretion.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Somatostatin Positive Control Slides , Product No. 332S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000047546
0000047545
0000045313
0000045314
0000045315

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M Quartu et al.
Journal of chemical neuroanatomy, 6(2), 79-99 (1993-03-01)
The occurrence of vasoactive intestinal polypeptide (VIP), peptide histidine-isoleucine (PHI), calcitonin gene-related peptide (CGRP), substance P (SP), somatostatin (SOM), galanin (GAL) and enkephalins (ENK) is studied in the human celiac/superior mesenteric ganglionic complex of pre- and full-term newborns, and adult
G Fried et al.
Cancer, 74(1), 142-151 (1994-07-01)
A case of a renin-producing paraganglioma of adrenal origin with metastases to the retroperitoneal area, paravaginal area, and the ovary is reported with immunohistochemical findings indicating expression of multiple neuropeptide immunoreactivities. The patient was 23 years old at the time
G Somers et al.
Gastroenterology, 85(5), 1192-1198 (1983-11-01)
A duodenal somatostatinoma is described in a patient suffering from a tumoral obstruction of the bile duct. The diagnosis was based upon histologic and immunocytochemical characterization of tumoral fragments and later confirmed by immunochemical analysis of liver metastases. Basal peripheral
G J Krejs et al.
The New England journal of medicine, 301(6), 285-292 (1979-08-09)
Diabetes mellitus, steatorrhea, cholelithiasis and a tumor distorting the duodenum prompted a work-up for somatostatinoma in a 52-year-old man. The responses of pancreatic B-cells but not of A-cells to nutrient stimuli were inhibited, and growth-hormone release was suppressed, suggesting somatostatin
Maria Angelova Tzaneva
Acta histochemica, 105(2), 191-201 (2003-07-02)
Five types of endocrine cells are found in the human antral gastric mucosa: gastrin (G) cells, somatostatin (D) cells, enterochromaffin (EC) cells and cells with an unknown secretory product (D1 cells and P cells). The content of secretory granules, gastrin
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