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32856

Sigma-Aldrich

May-Grünwald solution

according to May-Grünwald

Synonym(s):

Eosin – methylene blue solution, Eosin methylene blue according to May-Grünwald

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About This Item

EC Number:
200-659-6
MDL number:
MFCD00005038
UNSPSC Code:
12171500
PubChem Substance ID:
329754362

quality

according to May-Grünwald

suitability

passes test for UV spectrum

SMILES string

[K+].COC(=O)c1ccccc1C2=C3C=C(Br)C(=O)C(Br)=C3Oc4c(Br)c([O-])c(Br)cc24

InChI

1S/C21H10Br4O5.K/c1-29-21(28)9-5-3-2-4-8(9)14-10-6-12(22)17(26)15(24)19(10)30-20-11(14)7-13(23)18(27)16(20)25;/h2-7,26H,1H3;/q;+1/p-1

InChI key

NXBZXYJXNIFCRJ-UHFFFAOYSA-M

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General description

May-Grünwald-Giemsa (MGG) stain is a Romanowsky-type, polychromatic stain as those of Giemsa, Leishman and Wright. It is used as reference stain in haematology. It is also used as routine stain in diagnostic cytopathology for the study of air-dried preparations (centrifuged body fluids, lymph node imprints, and fine needle aspirations).

Application

May-Grünwald and Giemsa stain was used for staining polymorphonuclear cells, monocytes and lymphocytes, for differential leukocyte counts, during hematological analysis, in an experimental study conducted to study immune responses in the pathology of acute magnesium deficiency in rats. It was also used to stain cells from bronchoalveolar lavage (BAL) fluid, in an experimental investigation, done to study the role of Fas ligand in murine silicosis.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

53.6 °F

Flash Point(C)

12 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number
SZBE0800V
SZBC328BV
SZBC328B
SZBC075CV
SZBC075C

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Inflammatory response following acute magnesium deficiency in the rat.
Malpuech BC
Biochim. Biophys. Acta Gen. Subj., 1501 (2), 91-98 (2000)
Fas ligand triggers pulmonary silicosis.
Borges VM
The Journal of Experimental Medicine, 194 (2), 155-164 (2001)
Eric Piaton et al.
Annales de pathologie, 35(4), 294-305 (2015-07-21)
May-Grünwald-Giemsa (MGG) stain is a Romanowsky-type, polychromatic stain as those of Giemsa, Leishman and Wright. Apart being the reference method of haematology, it has become a routine stain of diagnostic cytopathology for the study of air-dried preparations (lymph node imprints
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